Varaico: Literature-Extracted Genetic Variants

Gene:NOTCH1
Variant:p.D469G
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NOTCH1

NM_017617.5:p.D469G

Associated Papers

Somatic mutation and selection at population scale.

Lawson ARJ et al.

Nature, 2025

41062696 (PubMed )
Supplement: 41586_2025_9584_MOESM6_ESM.xlsx › sitednds_oral

Multiscale simulations reveal architecture of NOTCH protein and ligand specific features.

Rathore S et al.

Biophysical Journal, 2025

Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.

Abby E et al.

Nature Genetics, 2023

36658434 (PubMed )
Supplement: 41588_2022_1280_MOESM4_ESM.xlsx › Sup_Table_19

Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy.

Findlay JM et al.

Nature Communications, 2016

27045317 (PubMed )
Supplement: ncomms11111-s1.pdf

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.

Wang NJ et al.

Proceedings of the National Academy of Sciences of the United States of America, 2011

Localization of the delta-like-1-binding site in human Notch-1 and its modulation by calcium affinity.

Cordle J et al.

The Journal of Biological Chemistry, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."