Varaico: Literature-Extracted Genetic Variants

Gene:NOTCH3
Variant:p.G2225del1
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NOTCH3

NM_000435.3:p.G2225del1

Associated Papers

Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.

Bernasconi-Elias P et al.

Oncogene, 2016

27157619 (PubMed )
Supplement: NIHMS766844-supplement-11.pdf

PEST domain mutations in Notch receptors comprise an oncogenic driver segment in triple-negative breast cancer sensitive to a γ-secretase inhibitor.

Wang K et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2015

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