Varaico: Literature-Extracted Genetic Variants

Gene:NPM1
Variant:p.W288C
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NPM1

NM_002520.7:p.W288C

Associated Papers

Risk prediction for clonal cytopenia: multicenter real-world evidence.

Xie Z et al.

Blood, 2024

38996210 (PubMed )
Supplement: BLOOD_BLD-2024-024756-mmc1.pdf

Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia.

Bruedigam C et al.

Nature Cancer, 2024

37904045 (PubMed )
Supplement: 43018_2023_653_MOESM22_ESM.xlsx › Extended_Data_Fig._9b

Mining cancer genomes for change-of-metabolic-function mutations.

Tu KJ et al.

Communications Biology, 2023

37950065 (PubMed )
Supplement: 42003_2023_5475_MOESM2_ESM.pdf

Mutation profile of acute myeloid leukaemia in a Chinese cohort by targeted next-generation sequencing.

Lit BMW et al.

Cancer Reports (hoboken, N.j.), 2022

Clinical significance of chromatin-spliceosome acute myeloid leukemia: a report from the Northern Italy Leukemia Group (NILG) randomized trial 02/06.

Caprioli C et al.

Haematologica, 2021

32855275 (PubMed )
Supplement: 2020_252825_CAPRIOLI_SUPPL.pdf

Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.

Simeoni F et al.

Cell Reports, 2021

34551306 (PubMed )
Supplement: mmc1.pdf

Comprehensive genetic diagnosis of acute myeloid leukemia by next-generation sequencing.

Mack EKM et al.

Haematologica, 2019

30190345 (PubMed )
Supplement: 2018.194258.MACK_SUPPL.pdf

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms.

Zhang H et al.

Nature Communications, 2019

30651561 (PubMed )
Supplement: 41467_2018_8263_MOESM5_ESM.xlsx › Supplementary_Data_2

Novel complex mutation in NPM1 gene in patient with acute myeloid leukemia.

Jeziskova I et al.

Leukemia & Lymphoma, 2017

Detection of minimal residual disease in NPM1-mutated acute myeloid leukemia by next-generation sequencing.

Salipante SJ et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2014

Role of cysteine 288 in nucleophosmin cytoplasmic mutations: sensitization to toxicity induced by arsenic trioxide and bortezomib.

Huang M et al.

Leukemia, 2013

Born to be exported: COOH-terminal nuclear export signals of different strength ensure cytoplasmic accumulation of nucleophosmin leukemic mutants.

Bolli N et al.

Cancer Research, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."