Varaico: Literature-Extracted Genetic Variants

Gene:NQO1
Variant:p.E247Q
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NQO1

NM_000903.3:p.E247Q

Associated Papers

NAD(P)H quinone oxidoreductase (NQO1): an enzyme which needs just enough mobility, in just the right places.

Pey AL et al.

Bioscience Reports, 2019

Evolutionary Divergent Suppressor Mutations in Conformational Diseases.

Mesa-Torres N et al.

Genes, 2018

Thermodynamics of cooperative binding of FAD to human NQO1: Implications to understanding cofactor-dependent function and stability of the flavoproteome.

Clavería-Gimeno R et al.

Archives of Biochemistry and Biophysics, 2017

Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution.

Medina-Carmona E et al.

Human Molecular Genetics, 2017

Mutagenesis of three conserved Glu residues in a bacterial homologue of the ND1 subunit of complex I affects ubiquinone reduction kinetics but not inhibition by dicyclohexylcarbodiimide.

Kurki S et al.

Biochemistry, 2000

NQO1: A target for the treatment of cancer and neurological diseases, and a model to understand loss of function disease mechanisms.

Beaver SK et al.

Biochimica Et Biophysica Acta. Proteins and Proteomics, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."