Varaico: Literature-Extracted Genetic Variants

Gene:NQO1
Variant:p.F117Y
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NQO1

NM_000903.3:p.F117Y

Associated Papers

Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response.

Ikeda R et al.

The Embo Journal, 2023

37306101 (PubMed )
Supplement: EMBJ-42-e113349-s011.pdf

Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show reduced inner fluidity.

Faruk MO et al.

The Journal of Biological Chemistry, 2021

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.

Jain A et al.

The Journal of Biological Chemistry, 2010

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