Associated Papers
Steroid-resistant nephrotic syndrome: pharmacogenetics and epigenetic points and views.
Hejazian SM et al.
Expert Review of Clinical Pharmacology, 2020
A comprehensive analysis and functional characterization of naturally occurring non-synonymous variants of nuclear receptor PXR.
Rana M et al.
Biochimica Et Biophysica Acta, 2016
Role of pregnane X receptor in chemotherapeutic treatment.
Zhuo W et al.
Cancer Chemotherapy and Pharmacology, 2014
Genetic variability of PXR in Saudi Arabians.
Al-Dosari MS et al.
Biochemical Genetics, 2013
Nuclear receptor-mediated induction of CYP450 by antiretrovirals: functional consequences of NR1I2 (PXR) polymorphisms and differential prevalence in whites and sub-Saharan Africans.
Svärd J et al.
Journal of Acquired Immune Deficiency Syndromes (1999), 2010
Identification of polymorphisms in the 3'-untranslated region of the human pregnane X receptor (PXR) gene associated with variability in cytochrome P450 3A (CYP3A) metabolism.
Oleson L et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2010
PXR pharmacogenetics: association of haplotypes with hepatic CYP3A4 and ABCB1 messenger RNA expression and doxorubicin clearance in Asian breast cancer patients.
Sandanaraj E et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2008
PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics.
Zhang B et al.
Pharmacogenomics, 2008
Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy.
Owen BM et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2008
PXR, CAR and HNF4alpha genotypes and their association with pharmacokinetics and pharmacodynamics of docetaxel and doxorubicin in Asian patients.
Hor SY et al.
The Pharmacogenomics Journal, 2008
Single nucleotide polymorphisms of the pregnane x receptor gene in Han Chinese and a comparison with other ethnic populations.
Wang XD et al.
Pharmacology, 2008
Identification of NR1I2 genetic variation using resequencing.
King CR et al.
European Journal of Clinical Pharmacology, 2007
Polymorphisms in the steroid and xenobiotic receptor gene influence survival in primary sclerosing cholangitis.
Karlsen TH et al.
Gastroenterology, 2006
Screening for polymorphisms in the PXR gene in a Dutch population.
Bosch TM et al.
European Journal of Clinical Pharmacology, 2006
Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes.
Okey AB et al.
Pharmacogenetics and Genomics, 2005
[Single nucleotide polymorphisms of growth hormone receptor gene in Chinese Han ethnic population].
Zhou J et al.
Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology, 2004
Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region.
Koyano S et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2004
The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.
Zhang J et al.
Pharmacogenetics, 2001
Hepatic OATP1B transporters and nuclear receptors PXR and CAR: interplay, regulation of drug disposition genes, and single nucleotide polymorphisms.
Meyer zu Schwabedissen HE et al.
Molecular Pharmaceutics, 0