Varaico: Literature-Extracted Genetic Variants

Gene:NR1I2
Variant:p.R127G
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NR1I2

NM_003889.4:p.R127G

Associated Papers

Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Aboul-Soud MAM et al.

Saudi Journal of Biological Sciences, 2021

33424349 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Targeted next generation sequencing as a tool for precision medicine.

Gulilat M et al.

Bmc Medical Genomics, 2019

31159795 (PubMed )
Supplement: 12920_2019_527_MOESM1_ESM.xlsx › Table_S6

A comprehensive analysis and functional characterization of naturally occurring non-synonymous variants of nuclear receptor PXR.

Rana M et al.

Biochimica Et Biophysica Acta, 2016

Role of pregnane X receptor in chemotherapeutic treatment.

Zhuo W et al.

Cancer Chemotherapy and Pharmacology, 2014

Nuclear receptor-mediated induction of CYP450 by antiretrovirals: functional consequences of NR1I2 (PXR) polymorphisms and differential prevalence in whites and sub-Saharan Africans.

Svärd J et al.

Journal of Acquired Immune Deficiency Syndromes (1999), 2010

Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy.

Owen BM et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2008

Screening for polymorphisms in the PXR gene in a Dutch population.

Bosch TM et al.

European Journal of Clinical Pharmacology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."