Associated Papers
A comprehensive analysis and functional characterization of naturally occurring non-synonymous variants of nuclear receptor PXR.
Rana M et al.
Biochimica Et Biophysica Acta, 2016
Tryptophan 299 is a conserved residue of human pregnane X receptor critical for the functional consequence of ligand binding.
Banerjee M et al.
Biochemical Pharmacology, 2016
PXR polymorphisms and their impact on pharmacokinetics/pharmacodynamics of repaglinide in healthy Chinese volunteers.
Du QQ et al.
European Journal of Clinical Pharmacology, 2013
Pregnane X receptor polymorphisms associated with human diseases.
Kotta-Loizou I et al.
Expert Opinion on Therapeutic Targets, 2013
Genetic variability of PXR in Saudi Arabians.
Al-Dosari MS et al.
Biochemical Genetics, 2013
Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem.
Klein K et al.
Frontiers in Genetics, 2013
PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics.
Zhang B et al.
Pharmacogenomics, 2008
Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy.
Owen BM et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2008
Single nucleotide polymorphisms of the pregnane x receptor gene in Han Chinese and a comparison with other ethnic populations.
Wang XD et al.
Pharmacology, 2008
Identification of NR1I2 genetic variation using resequencing.
King CR et al.
European Journal of Clinical Pharmacology, 2007
Screening for polymorphisms in the PXR gene in a Dutch population.
Bosch TM et al.
European Journal of Clinical Pharmacology, 2006
Functional characterization of a novel polymorphism of pregnane X receptor, Q158K, in Chinese subjects.
Lim YP et al.
Pharmacogenetics and Genomics, 2005
[Single nucleotide polymorphisms of growth hormone receptor gene in Chinese Han ethnic population].
Zhou J et al.
Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology, 2004
Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region.
Koyano S et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2004
Hepatic OATP1B transporters and nuclear receptors PXR and CAR: interplay, regulation of drug disposition genes, and single nucleotide polymorphisms.
Meyer zu Schwabedissen HE et al.
Molecular Pharmaceutics, 0