Varaico: Literature-Extracted Genetic Variants

Gene:NR1I2
Variant:p.Q158K
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NR1I2

NM_003889.4:p.Q158K

Associated Papers

Differential Effects of Components in Artemisia annua Extract on the Induction of Drug-Metabolizing Enzyme Expression Mediated by Nuclear Receptors.

Zhang X et al.

Planta Medica, 2020

A comprehensive analysis and functional characterization of naturally occurring non-synonymous variants of nuclear receptor PXR.

Rana M et al.

Biochimica Et Biophysica Acta, 2016

Role of pregnane X receptor in chemotherapeutic treatment.

Zhuo W et al.

Cancer Chemotherapy and Pharmacology, 2014

PXR polymorphisms and their impact on pharmacokinetics/pharmacodynamics of repaglinide in healthy Chinese volunteers.

Du QQ et al.

European Journal of Clinical Pharmacology, 2013

Genetic variability of PXR in Saudi Arabians.

Al-Dosari MS et al.

Biochemical Genetics, 2013

PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics.

Zhang B et al.

Pharmacogenomics, 2008

Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy.

Owen BM et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2008

Single nucleotide polymorphisms of the pregnane x receptor gene in Han Chinese and a comparison with other ethnic populations.

Wang XD et al.

Pharmacology, 2008

Pregnane X receptor polymorphism affects CYP3A4 induction via a ligand-dependent interaction with steroid receptor coactivator-1.

Lim YP et al.

Pharmacogenetics and Genomics, 2007

CYP3A phenotypes and genotypes in North Indians.

Rais N et al.

European Journal of Clinical Pharmacology, 2006

Functional characterization of a novel polymorphism of pregnane X receptor, Q158K, in Chinese subjects.

Lim YP et al.

Pharmacogenetics and Genomics, 2005

[Single nucleotide polymorphisms of growth hormone receptor gene in Chinese Han ethnic population].

Zhou J et al.

Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."