Varaico: Literature-Extracted Genetic Variants

Gene:NR1I2
Variant:p.G313Splc
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NR1I2

NM_003889.4:p.G313Splc

Associated Papers

Pregnane X Receptor (PXR) Polymorphisms and Cancer Treatment.

Skandalaki A et al.

Biomolecules, 2021

PXR haplotype clusters will affect the pharmacokinetics of ciclosporin in Chinese renal transplant recipients.

Li D et al.

The Journal of Pharmacy and Pharmacology, 2020

Genetic factors affecting drug disposition in Asian cancer patients.

Syn NL et al.

Expert Opinion on Drug Metabolism & Toxicology, 2015

Pregnane X receptor and hepatocyte nuclear factor 4α polymorphisms are cooperatively associated with carbamazepine autoinduction.

Saruwatari J et al.

Pharmacogenetics and Genomics, 2014

Pharmacogenetic effects of regulatory nuclear receptors (PXR, CAR, RXRα and HNF4α) on docetaxel disposition in Chinese nasopharyngeal cancer patients.

Chew SC et al.

European Journal of Clinical Pharmacology, 2014

The effect of fetal androgen metabolism-related gene variants on external genitalia virilization in congenital adrenal hyperplasia.

Kaupert LC et al.

Clinical Genetics, 2013

Role of pharmacogenetics on adjuvant chemotherapy-induced neutropenia in Chinese breast cancer patients.

Tang NL et al.

Journal of Cancer Research and Clinical Oncology, 2013

Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem.

Klein K et al.

Frontiers in Genetics, 2013

Effects of pregnane X receptor (NR1I2) and CYP2B6 genetic polymorphisms on the induction of bupropion hydroxylation by rifampin.

Chung JY et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2011

PXR pharmacogenetics: association of haplotypes with hepatic CYP3A4 and ABCB1 messenger RNA expression and doxorubicin clearance in Asian breast cancer patients.

Sandanaraj E et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."