Varaico: Literature-Extracted Genetic Variants

Gene:NR2C2
Variant:p.K34R
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NR2C2

NM_001291694.2:p.K34R

Associated Papers

TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation.

Mao R et al.

Cellular Signalling, 2011

TTRAP is a novel component of the non-canonical TRAF6-TAK1 TGF-β signaling pathway.

Várady G et al.

Plos One, 2011

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner.

Sorrentino A et al.

Nature Cell Biology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."