Varaico: Literature-Extracted Genetic Variants

Gene:NR3C1
Variant:p.Q710*
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NR3C1

NM_000176.3:p.Q710*

Associated Papers

Loss of heterozygosity and somatic mutations of the glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course.

Irving JA et al.

Cancer Research, 2005

Variations of the human glucocorticoid receptor gene (NR3C1): pathological and in vitro mutations and polymorphisms.

Bray PJ et al.

Human Mutation, 2003

Glucocorticoid-receptor-gene defects and resistance to glucocorticoid-induced apoptosis in human leukemic cell lines.

Hala M et al.

International Journal of Cancer, 1996

Splice site mutation in the glucocorticoid receptor gene causes resistance to glucocorticoid-induced apoptosis in a human acute leukemic cell line.

Strasser-Wozak EM et al.

Cancer Research, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."