Varaico: Literature-Extracted Genetic Variants

Gene:NR3C1
Variant:p.S226A
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NR3C1

NM_000176.3:p.S226A

Associated Papers

O-GlcNAc transferase promotes immune evasion and immunotherapy resistance in uterine corpus endometrial cancer by targeting the glucocorticoid receptor.

Wang J et al.

Journal for Immunotherapy of Cancer, 2025

Site-specific phosphorylation regulates the structure and function of an intrinsically disordered domain of the glucocorticoid receptor.

Khan SH et al.

Scientific Reports, 2017

Role of ligand-dependent GR phosphorylation and half-life in determination of ligand-specific transcriptional activity.

Avenant C et al.

Molecular and Cellular Endocrinology, 2010

Recruitment of cAMP-response element-binding protein and histone deacetylase has opposite effects on glucocorticoid receptor gene transcription.

Govindan MV

The Journal of Biological Chemistry, 2010

Glucocorticoid receptor phosphorylation modulates transcription efficacy through GRIP-1 recruitment.

Avenant C et al.

Biochemistry, 2010

Differential regulation of the transcriptional activity of the glucocorticoid receptor through site-specific phosphorylation.

Kumar R et al.

Biologics : Targets & Therapy, 2008

Glucocorticoid receptor phosphorylation differentially affects target gene expression.

Chen W et al.

Molecular Endocrinology (baltimore, Md.), 2008

Cyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: clinical implications for the nervous system response to glucocorticoids and stress.

Kino T et al.

Molecular Endocrinology (baltimore, Md.), 2007

Modulation of glucocorticoid receptor phosphorylation and transcriptional activity by a C-terminal-associated protein phosphatase.

Wang Z et al.

Molecular Endocrinology (baltimore, Md.), 2007

Modulation of glucocorticoid receptor function via phosphorylation.

Ismaili N et al.

Annals of the New York Academy of Sciences, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."