Varaico: Literature-Extracted Genetic Variants

Gene:NR3C2
Variant:p.T945A
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NR3C2

NM_000901.5:p.T945A

Associated Papers

Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1.

Amazit L et al.

The Journal of Biological Chemistry, 2015

A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor.

Bledsoe RK et al.

The Journal of Biological Chemistry, 2005

Mechanistic aspects of mineralocorticoid receptor activation.

Hellal-Levy C et al.

Kidney International, 2000

Antagonism in the human mineralocorticoid receptor.

Fagart J et al.

The Embo Journal, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."