Associated Papers
In Silico Investigation of Mineralocorticoid Receptor Antagonists: Insights into Binding Mechanisms and Structural Dynamics.
Liang JJ et al.
Molecules (basel, Switzerland), 2025
Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor β.
Yao B et al.
Journal of Molecular Biology, 2020
Crystal structure of the mineralocorticoid receptor ligand-binding domain in complex with a potent and selective nonsteroidal blocker, esaxerenone (CS-3150).
Takahashi M et al.
Febs Letters, 2020
Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1.
Amazit L et al.
The Journal of Biological Chemistry, 2015
A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor.
Bledsoe RK et al.
The Journal of Biological Chemistry, 2005
Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor.
Li Y et al.
Molecular Cell, 2005
Cysteines 849 and 942 of human mineralocorticoid receptor are crucial for steroid binding.
Lupo B et al.
Biochemistry, 1998
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