Varaico: Literature-Extracted Genetic Variants

Gene:NR3C2
Variant:p.A773G
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NR3C2

NM_000901.5:p.A773G

Associated Papers

Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1.

Amazit L et al.

The Journal of Biological Chemistry, 2015

A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor.

Bledsoe RK et al.

The Journal of Biological Chemistry, 2005

Mutation of the androgen receptor at amino acid 708 (Gly-->Ala) abolishes partial agonist activity of steroidal antiandrogens.

Terouanne B et al.

Molecular Pharmacology, 2003

Antimineralocorticoid 11beta-substituted spirolactones exhibit androgen receptor agonistic activity: a structure function study.

Nirdé P et al.

Molecular Pharmacology, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."