Varaico: Literature-Extracted Genetic Variants

Gene:NRAS
Variant:p.K135R
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NRAS

NM_002524.5:p.K135R

Associated Papers

Pharmacological targeting of casein kinase 1δ suppresses oncogenic NRAS-driven melanoma.

Wen Y et al.

Nature Communications, 2024

Inhibition and degradation of NRAS with a pan-NRAS monobody.

Whaby M et al.

Oncogene, 2024

K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins.

Magits W et al.

The Embo Journal, 2024

38858602 (PubMed )
Supplement: 44318_2024_146_MOESM1_ESM.pdf

Identification and analysis of oncogenic non-synonymous single nucleotide polymorphisms in the human NRAS gene: An exclusive in silico study.

Mozibullah M et al.

Journal, Genetic Engineering & Biotechnology, 2024

38797553 (PubMed )
Supplement: mmc1.xlsx › Table_1

Structural bioinformatics enhances mechanistic interpretation of genomic variation, demonstrated through the analyses of 935 distinct RAS family mutations.

Tripathi S et al.

Bioinformatics (oxford, England), 2021

33226070 (PubMed )
Supplement: btaa972_supplementary_data.zip › RAS_Manuscript_RMarkdown.tar.gz › RAS_Manuscript1.Revised › RAS_Variants_Scores.xlsx › Sheet1

Gene mutations in stool from gastric and colorectal neoplasia patients by next-generation sequencing.

Youssef O et al.

World Journal of Gastroenterology, 2017

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