Varaico: Literature-Extracted Genetic Variants

Gene:NRAS
Variant:p.K128R
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NRAS

NM_002524.5:p.K128R

Associated Papers

Pharmacological targeting of casein kinase 1δ suppresses oncogenic NRAS-driven melanoma.

Wen Y et al.

Nature Communications, 2024

39572526 (PubMed )
Supplement: 41467_2024_54140_MOESM1_ESM.pdf

K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins.

Magits W et al.

The Embo Journal, 2024

38858602 (PubMed )
Supplement: 44318_2024_146_MOESM2_ESM.pdf
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