Varaico: Literature-Extracted Genetic Variants

Gene:NRAS
Variant:p.C118S
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NRAS

NM_002524.5:p.C118S

Associated Papers

Revealing conformational changes of GTP-bound NRAS mutants probed by GaMD and Markov state models.

Zhao L et al.

Physical Chemistry Chemical Physics : Pccp, 2026

K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins.

Magits W et al.

The Embo Journal, 2024

38858602 (PubMed )
Supplement: 44318_2024_146_MOESM1_ESM.pdf

Exploring conformation changes of Janus kinase 2 pseudokinase mediated by mutations through Gaussian accelerated molecular dynamics and principal component analysis.

Bao H et al.

Journal of Biomolecular Structure & Dynamics, 2024

Deciphering Conformational Changes of the GDP-Bound NRAS Induced by Mutations G13D, Q61R, and C118S through Gaussian Accelerated Molecular Dynamic Simulations.

Yu Z et al.

Molecules (basel, Switzerland), 2022

Cysteine-based regulation of redox-sensitive Ras small GTPases.

Messina S et al.

Redox Biology, 2019

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