Varaico: Literature-Extracted Genetic Variants

Gene:NRAS
Variant:p.Y96C
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NRAS

NM_002524.5:p.Y96C

Associated Papers

Identification and analysis of oncogenic non-synonymous single nucleotide polymorphisms in the human NRAS gene: An exclusive in silico study.

Mozibullah M et al.

Journal, Genetic Engineering & Biotechnology, 2024

38797553 (PubMed )
Supplement: mmc1.xlsx › Table_1

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.

Holderfield M et al.

Nature, 2024

38589574 (PubMed )
Supplement: 41586_2024_7205_MOESM5_ESM.xlsx › ED_Fig_10

Targeting RAS mutants in malignancies: successes, failures, and reasons for hope.

Yang H et al.

Cancer Communications (london, England), 2023

Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C.

Weiss A et al.

Cancer Discovery, 2022

35404998 (PubMed )
Supplement: cd-22-0158_supplementary_tables_suppst1-st7.docx

Oncogenic KRAS blockade therapy: renewed enthusiasm and persistent challenges.

Tang D et al.

Molecular Cancer, 2021

Blockade of mutant RAS oncogenic signaling with a special emphasis on KRAS.

Roskoski R

Pharmacological Research, 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."