Varaico: Literature-Extracted Genetic Variants

Gene:NRAS
Variant:p.I55_S65ins3
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NRAS

NM_002524.5:p.I55_S65ins3

Associated Papers

Erdheim-Chester Disease Due to a Novel Internal Duplication of NRAS: Response to Targeted Therapy with Cobimetinib.

Riancho JA et al.

International Journal of Molecular Sciences, 2023

RAS internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling.

Nelson AC et al.

The Journal of Biological Chemistry, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."