Varaico: Literature-Extracted Genetic Variants

Gene:NRG1
Variant:p.R38Q
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NRG1

NM_013964.5:p.R38Q

Associated Papers

Patient tissue-derived FGFR4-variant and wild-type colorectal cancer organoid development and anticancer drug sensitivity testing.

Lin H et al.

Heliyon, 2024

38826758 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_1

A Patient with MELAS Syndrome Carried an M.3243A>G Mutation in Mitochondrial DNA and Multiple Nuclear Genetic Variants: A Case Report.

Chu X et al.

Iranian Journal of Public Health, 2022

Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity.

Yoshizawa T et al.

Npj Precision Oncology, 2021

33863983 (PubMed )
Supplement: 41698_2021_170_MOESM4_ESM.xlsx › Pre_Post_Afatinibshared_variant

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.

Nagasawa S et al.

Communications Biology, 2021

33795819 (PubMed )
Supplement: 42003_2021_1959_MOESM5_ESM.xlsx › CaseB

Genetic Determinants of Gating Functions: Do We Get Closer to Understanding Schizophrenia Etiopathogenesis?

Rovný R et al.

Frontiers in Psychiatry, 2020

33324248 (PubMed )
Supplement: Data_Sheet_1.docx

The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models.

Katayama R et al.

Nature Communications, 2019

31399568 (PubMed )
Supplement: 41467_2019_11496_MOESM4_ESM.xlsx › JFCR-165_mutations

Meta-analysis reveals associations between genetic variation in the 5' and 3' regions of Neuregulin-1 and schizophrenia.

Mostaid MS et al.

Translational Psychiatry, 2017

28094814 (PubMed )
Supplement: tp2016279x1.docx

Association of the DISC1 and NRG1 genetic polymorphisms with schizophrenia in a Chinese population.

He BS et al.

Gene, 2016

Genetic association between NRG1 and schizophrenia, major depressive disorder, bipolar disorder in Han Chinese population.

Wen Z et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2016

Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes.

Deschamps M et al.

American Journal of Human Genetics, 2016

Genetic assessment of additional endophenotypes from the Consortium on the Genetics of Schizophrenia Family Study.

Greenwood TA et al.

Schizophrenia Research, 2016

Generation and characterization of humanized mice carrying COMT158 Met/Val alleles.

Risbrough V et al.

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2014

Association between a Missense Polymorphism (rs3924999, Arg253Gln) of Neuregulin 1 and Schizophrenia in Korean Population.

Yang SA

Experimental Neurobiology, 2012

Sensorimotor gating and D2 receptor signalling: evidence from a molecular genetic approach.

Völter C et al.

The International Journal of Neuropsychopharmacology, 2012

Missense substitutions associated with behavioural disturbances in Alzheimer's disease (AD).

Proitsi P et al.

Brain Research Bulletin, 2012

Lack of associations of neuregulin 1 variations with schizophrenia and smooth pursuit eye movement abnormality in a Korean population.

Kim JH et al.

Journal of Molecular Neuroscience : Mn, 2012

Association analysis of 94 candidate genes and schizophrenia-related endophenotypes.

Greenwood TA et al.

Plos One, 2012

Variation in genes involved in dopamine clearance influence the startle response in older adults.

Armbruster D et al.

Journal of Neural Transmission (vienna, Austria : 1996), 2011

Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia.

Greenwood TA et al.

The American Journal of Psychiatry, 2011

The association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males.

Roussos P et al.

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2011

Sensorimotor gating is associated with CHRNA3 polymorphisms in schizophrenia and healthy volunteers.

Petrovsky N et al.

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2010

Sensorimotor gating depends on polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase, but not on neuregulin-1 Arg38Gln genotype: a replication study.

Quednow BB et al.

Biological Psychiatry, 2009

Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia.

Li D et al.

Human Molecular Genetics, 2006

Analysis of polymorphisms in AT-rich domains of neuregulin 1 gene in schizophrenia.

Lachman HM et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2006

Neuregulin-1 polymorphism in late onset Alzheimer's disease families with psychoses.

Go RC et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2005

Association between the neuregulin 1 gene and schizophrenia: a systematic review.

Tosato S et al.

Schizophrenia Bulletin, 2005

Finding schizophrenia genes.

Kirov G et al.

The Journal of Clinical Investigation, 2005

Case-control and family-based association studies between the neuregulin 1 (Arg38Gln) polymorphism and schizophrenia.

Hong CJ et al.

Neuroscience Letters, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."