Varaico: Literature-Extracted Genetic Variants

Gene:NSUN2
Variant:p.L91I
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NSUN2

NM_017755.6:p.L91I

Associated Papers

Copy number amplification of TTPAL promotes cholesterol biosynthesis and esophageal squamous cell carcinoma progression via elevating NSUN2-mediated m5C modification of SREBP2 mRNA.

Huang S et al.

Journal of Experimental & Clinical Cancer Research : Cr, 2025

Liu L et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2024

Chemical Proteomic Discovery of Isotype-Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2.

Tao Y et al.

Angewandte Chemie (international Ed. in English), 2023

YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA.

Dai X et al.

Analytical Chemistry, 2020

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs.

Chen X et al.

Nature Cell Biology, 2019

Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation.

Sajini AA et al.

Nature Communications, 2019

5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C reader.

Yang X et al.

Cell Research, 2017

28418038 (PubMed )
Supplement: cr201755x12.xlsx › Primers_for_cloning

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.

Blanco S et al.

The Embo Journal, 2014

NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs.

Hussain S et al.

Cell Reports, 2013

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability.

Hussain S et al.

The Journal of Cell Biology, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."