Varaico: Literature-Extracted Genetic Variants

Gene:NT5C2
Variant:p.S445F
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NT5C2

NM_001351169.2:p.S445F

Associated Papers

Molecular Profiling Reveals Novel Gene Fusions and Genetic Markers for Refined Patient Stratification in Pediatric Acute Lymphoblastic Leukemia.

Péterffy B et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2025

Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia.

Barz MJ et al.

Blood, 2020

Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.

Dieck CL et al.

Cancer Cell, 2018

Integrated Molecular Characterization of Gastrointestinal Stromal Tumors (GIST) Harboring the Rare D842V Mutation in PDGFRA Gene.

Indio V et al.

International Journal of Molecular Sciences, 2018

29510530 (PubMed )
Supplement: ijms-19-00732-s001.xlsx › Supplementary_Table_4

Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia.

Hnízda A et al.

Bmc Biology, 2016

Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia.

Meyer JA et al.

Nature Genetics, 2013

Therapeutic resistance: ALL-important mutations.

Seton-Rogers S

Nature Reviews. Cancer, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."