Varaico: Literature-Extracted Genetic Variants

Gene:NT5C2
Variant:p.S408R
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NT5C2

NM_001351169.2:p.S408R

Associated Papers

Leveraging genomic diagnostics for prognostics and therapeutics in pediatric acute leukemia.

Newman H et al.

Hemasphere, 2025

41306327 (PubMed )
Supplement: HEM3-9-e70269-s013.xlsx › Supplemental_Table_5_-_SSVs

Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia.

Li B et al.

Blood, 2020

Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.

Dieck CL et al.

Cancer Cell, 2018

Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.

Hnízda A et al.

Leukemia, 2018

Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia.

Hnízda A et al.

Bmc Biology, 2016

Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia.

Ma X et al.

Nature Communications, 2015

Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia.

Meyer JA et al.

Nature Genetics, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."