Varaico: Literature-Extracted Genetic Variants

Gene:NT5C2
Variant:p.R238L
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NT5C2

NM_001351169.2:p.R238L

Associated Papers

Preferential Genetic Pathways Lead to Relapses in Adult B-Cell Acute Lymphoblastic Leukemia.

Navas-Acosta J et al.

Cancers, 2024

Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia.

Barz MJ et al.

Blood, 2020

Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia.

Hnízda A et al.

Bmc Biology, 2016

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

Tzoneva G et al.

Nature Medicine, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."