Associated Papers
NUDT15 Pharmacogenetics in Acute Lymphoblastic Leukemia: Synthesizing Progress for Personalized Thiopurine Therapy.
Lubis IS et al.
Medical Sciences (basel, Switzerland), 2025
Genetic profiling of NUDT15 in the Slovenian population.
Šmid A et al.
Pharmacogenomics, 2024
A direct sequencing assay for pharmacogenetic testing of thiopurine-intolerant NUDT15 alleles in an Asian population.
Poon KS et al.
Bmc Research Notes, 2022
Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.
Lanillos J et al.
Npj Genomic Medicine, 2022
TPMT and NUDT15 testing for thiopurine therapy: A major tertiary hospital experience and lessons learned.
Goh LL et al.
Frontiers in Pharmacology, 2022
Importance of NUDT15 Polymorphisms in Thiopurine Treatments.
Tanaka Y et al.
Journal of Personalized Medicine, 2021
Childhood acute lymphoblastic leukemia mercaptopurine intolerance is associated with NUDT15 variants.
Wang DS et al.
Pediatric Research, 2021
Promising genes and variants to reduce chemotherapy adverse effects in acute lymphoblastic leukemia.
Bárcenas-López DA et al.
Translational Oncology, 2021
Comprehensive Custom NGS Panel Validation for the Improvement of the Stratification of B-Acute Lymphoblastic Leukemia Patients.
Montaño A et al.
Journal of Personalized Medicine, 2020
NUDT15 gene variants and thiopurine-induced leukopenia in patients with inflammatory bowel disease.
Matsuoka K
Intestinal Research, 2020
Thiopurine-mediated impairment of hematopoietic stem and leukemia cells in Nudt15R138C knock-in mice.
Tatsumi G et al.
Leukemia, 2020
Pharmacogene Variation Consortium Gene Introduction: NUDT15.
Yang JJ et al.
Clinical Pharmacology and Therapeutics, 2019
[Significance of NUDT15 gene in individualized treatment with 6-mercaptopurine in children with acute lymphoblastic leukemia].
He J et al.
Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics, 2019
Diplotype analysis of NUDT15 variants and 6-mercaptopurine sensitivity in pediatric lymphoid neoplasms.
Tsujimoto S et al.
Leukemia, 2018
NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.
Kakuta Y et al.
Journal of Gastroenterology, 2018
Pharmacogenetics of thiopurines for inflammatory bowel disease in East Asia: prospects for clinical application of NUDT15 genotyping.
Kakuta Y et al.
Journal of Gastroenterology, 2018
Influence of NUDT15 variants on hematological pictures of patients with inflammatory bowel disease treated with thiopurines.
Kojima Y et al.
World Journal of Gastroenterology, 2018
Emerging role of NUDT15 polymorphisms in 6-mercaptopurine metabolism and dose related toxicity in acute lymphoblastic leukaemia.
Singh M et al.
Leukemia Research, 2017
Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry.
Moriyama T et al.
Blood, 2017