Varaico: Literature-Extracted Genetic Variants

Gene:NUDT15
Variant:p.G47R
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NUDT15

NM_018283.4:p.G47R

Associated Papers

Validation of diagnostic screening test for pharmacogenomic targets for thiopurine drugs in indian pediatric acute lymphoblastic leukemia patients.

Joseph GT et al.

Frontiers in Pharmacology, 2025

Genetic profiling of NUDT15 in the Slovenian population.

Šmid A et al.

Pharmacogenomics, 2024

The Effect of NUDT15, TPMT, APEX1, and ITPA Genetic Variations on Mercaptopurine Treatment of Pediatric Acute Lymphoblastic Leukemia.

Lee JM et al.

Children (basel, Switzerland), 2021

NUDT15 gene variants and thiopurine-induced leukopenia in patients with inflammatory bowel disease.

Matsuoka K

Intestinal Research, 2020

Thiopurine-mediated impairment of hematopoietic stem and leukemia cells in Nudt15R138C knock-in mice.

Tatsumi G et al.

Leukemia, 2020

Pharmacogene Variation Consortium Gene Introduction: NUDT15.

Yang JJ et al.

Clinical Pharmacology and Therapeutics, 2019

30515762 (PubMed )
Supplement: CPT-105-1091-s001.xlsx › NUDT15_nomenclature_

NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.

Kakuta Y et al.

Journal of Gastroenterology, 2018

Pharmacogenetics of thiopurines for inflammatory bowel disease in East Asia: prospects for clinical application of NUDT15 genotyping.

Kakuta Y et al.

Journal of Gastroenterology, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."