Associated Papers
Pharmacogenetic Analysis of TPMT and NUDT15 in a European Pediatric Cohort with IBD and Autoimmune Diseases: Frequency Data and Clinical Relevance.
Pau A et al.
Genes, 2025
Large-Scale Pharmacogenomics Analysis of Patients With Cancer Within the 100,000 Genomes Project Combining Whole-Genome Sequencing and Medical Records to Inform Clinical Practice.
Leong IUS et al.
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2025
Gene polymorphisms associated with immunosuppressant adverse effects in systemic lupus erythematosus: a narrative review.
Hamdani S et al.
Frontiers in Genetics, 2025
Higher prevalence of NUDT15 rs116855232 compared to TPMT rs1142345 in a Chinese cohort and its implications for thiopurine therapy.
Zhao C et al.
Frontiers in Pharmacology, 2025
Clinical Benefits and Utility of Pretherapeutic DPYD and UGT1A1 Testing in Gastrointestinal Cancer: A Secondary Analysis of the PREPARE Randomized Clinical Trial.
Roncato R et al.
Jama Network Open, 2024
A Simple, Rapid, and Cost-Effective PCR Procedure for Detection of NUDT15 Gene Variants in Vietnamese Patients with Acute Lymphoblastic Leukemia.
Tram DB et al.
Journal of Laboratory Physicians, 2023
Allele-specific polymerase chain reaction can determine the diplotype of NUDT15 variants in patients with childhood acute lymphoblastic Leukemia.
Yu CH et al.
Scientific Reports, 2023
Population-Specific Distribution of TPMT Deficiency Variants and Ancestry Proportions in Ecuadorian Ethnic Groups: Towards Personalized Medicine.
Gallardo-Cóndor J et al.
Therapeutics and Clinical Risk Management, 2023
Nudix hydrolase 15 (NUDT15) loss-of-function variants in an Australian inflammatory bowel disease population.
Afrin S et al.
Internal Medicine Journal, 2022
A direct sequencing assay for pharmacogenetic testing of thiopurine-intolerant NUDT15 alleles in an Asian population.
Poon KS et al.
Bmc Research Notes, 2022
NUDT15 Genetic Variants in Chinese Han, Uighur, Kirghiz, and Dai Nationalities.
Zhang F et al.
Frontiers in Pediatrics, 2022
Nudix Hydroxylase 15 Mutations Strongly Predict Thiopurine-Induced Leukopenia Across Different Asian Ethnicities: Implications for Screening in a Diverse Population.
Khoo XH et al.
Frontiers in Medicine, 2022
Importance of NUDT15 Polymorphisms in Thiopurine Treatments.
Tanaka Y et al.
Journal of Personalized Medicine, 2021
The Effect of NUDT15, TPMT, APEX1, and ITPA Genetic Variations on Mercaptopurine Treatment of Pediatric Acute Lymphoblastic Leukemia.
Lee JM et al.
Children (basel, Switzerland), 2021
Cost-effectiveness analysis of pretreatment screening for NUDT15 defective alleles.
Zarca K et al.
Pharmacogenetics and Genomics, 2020
Association of NUDT15*3 and FPGS 2572C>T Variants with the Risk of Early Hematologic Toxicity During 6-MP and Low-Dose Methotrexate-Based Maintenance Therapy in Indian Patients with Acute Lymphoblastic Leukemia.
Kodidela S et al.
Genes, 2020
Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry.
Schaeffeler E et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2019
Pharmacogene Variation Consortium Gene Introduction: NUDT15.
Yang JJ et al.
Clinical Pharmacology and Therapeutics, 2019