Associated Papers
TIRR regulates mRNA export and association with P-bodies in response to DNA damage.
Glossop MS et al.
Nucleic Acids Research, 2024
DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation.
Ketley RF et al.
Cell Reports, 2022
The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair.
Luessing J et al.
Cell Reports, 2021
TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs.
Parnandi N et al.
Molecular Cell, 2021
Molecular basis for the inhibition of the methyl-lysine binding function of 53BP1 by TIRR.
Wang J et al.
Nature Communications, 2018
Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Botuyan MV et al.
Nature Structural & Molecular Biology, 2018
Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR.
Dai Y et al.
Nature Communications, 2018
TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.
Drané P et al.
Nature, 2017
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