Associated Papers
Dissecting the Mechanisms Underlying Substrate Recognition and Functional Regulation of O-GlcNAc Cycling Enzymes.
Hong ZZ et al.
Acs Chemical Biology, 2025
Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms.
Hansen SB et al.
Nature Communications, 2025
OGA mutant aberrantly hydrolyzes O-GlcNAc modification from PDLIM7 to modulate p53 and cytoskeleton in promoting cancer cell malignancy.
Hu CW et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024
Cancer-derived mutation in the OGA stalk domain promotes cell malignancy through dysregulating PDLIM7 and p53.
Hu CW et al.
Research Square, 2023
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