Varaico: Literature-Extracted Genetic Variants

Gene:OGG1
Variant:p.A53T
Back to variants list

OGG1

NM_002542.6:p.A53T

Associated Papers

The OGG1 Ser326Cys polymorphism: molecular mechanisms of disease susceptibility and precision medicine applications.

Wang X et al.

Clinical Epigenetics, 2025

Molecular Duality of OGG1: From Genomic Guardian to Redox-Sensitive Modulator in Diseases.

Zhong R et al.

Antioxidants (basel, Switzerland), 2025

The Link Between Human Alkyladenine DNA Glycosylase and Cancer Development.

Kladova OA et al.

International Journal of Molecular Sciences, 2025

Defective DNA repair: a putative nexus linking immunological diseases, neurodegenerative disorders, and cancer.

Andarawi S et al.

Mutagenesis, 2025

Activated or Impaired: An Overview of DNA Repair in Neurodegenerative Diseases.

Qin N et al.

Aging and Disease, 2022

Contributions of DNA Damage to Alzheimer's Disease.

Lin X et al.

International Journal of Molecular Sciences, 2020

DNA repair gene OGG1 polymorphism and its relation with oxidative DNA damage in patients with Alzheimer's disease.

Dinçer Y et al.

Neuroscience Letters, 2019

Investigation of base excision repair gene variants in late-onset Alzheimer's disease.

Ertuzun T et al.

Plos One, 2019

Current Concepts of Neurodegenerative Mechanisms in Alzheimer's Disease.

Magalingam KB et al.

Biomed Research International, 2018

Single nucleotide polymorphisms in DNA glycosylases: From function to disease.

D'Errico M et al.

Free Radical Biology & Medicine, 2017

Genome instability in Alzheimer disease.

Hou Y et al.

Mechanisms of Ageing and Development, 2017

Alzheimer's disease-associated polymorphisms in human OGG1 alter catalytic activity and sensitize cells to DNA damage.

Jacob KD et al.

Free Radical Biology & Medicine, 2013

Variation in base excision repair capacity.

Wilson DM et al.

Mutation Research, 2011

Variants and polymorphisms of DNA base excision repair genes and Alzheimer's disease.

Coppedè F

Journal of the Neurological Sciences, 2011

Evidence linking genetics, environment, and epigenetics to impaired DNA repair in Alzheimer's disease.

Coppedè F et al.

Journal of Alzheimer's Disease : Jad, 2010

Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase.

Sidorenko VS et al.

The Febs Journal, 2009

Identification and characterization of OGG1 mutations in patients with Alzheimer's disease.

Mao G et al.

Nucleic Acids Research, 2007

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."