Associated Papers
OGG1 augments the transcriptional activation of Foxp3 to promote iTreg differentiation for IBD alleviation.
Tian M et al.
Proceedings of the National Academy of Sciences of the United States of America, 2025
Contributing factors to the oxidation-induced mutational landscape in human cells.
Cordero C et al.
Nature Communications, 2024
Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles.
Ren M et al.
Nature Communications, 2024
Aberrant Repair of 8-Oxoguanine in Short DNA Bulges.
Eroshenko DA et al.
Doklady. Biochemistry and Biophysics, 2023
Differential Binding of NLRP3 to non-oxidized and Ox-mtDNA mediates NLRP3 Inflammasome Activation.
Cabral A et al.
Communications Biology, 2023
Single-molecule analysis of DNA-binding proteins from nuclear extracts (SMADNE).
Schaich MA et al.
Nucleic Acids Research, 2023
8-Oxoguanine: from oxidative damage to epigenetic and epitranscriptional modification.
Hahm JY et al.
Experimental & Molecular Medicine, 2022
Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.
Michel M et al.
Science (new York, N.y.), 2022
Genome-wide mapping of genomic DNA damage: methods and implications.
Amente S et al.
Cellular and Molecular Life Sciences : Cmls, 2021
Dynamic Processing of a Common Oxidative DNA Lesion by the First Two Enzymes of the Base Excision Repair Pathway.
Raper AT et al.
Journal of Molecular Biology, 2021
The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase.
Shigdel UK et al.
Nature Communications, 2020
Enzymatically inactive OGG1 binds to DNA and steers base excision repair toward gene transcription.
Hao W et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2020
Catalytically Competent Conformation of the Active Site of Human 8-Oxoguanine-DNA Glycosylase.
Popov AV et al.
Biochemistry. Biokhimiia, 2020
Roles of Active-Site Amino Acid Residues in Specific Recognition of DNA Lesions by Human 8-Oxoguanine-DNA Glycosylase (OGG1).
Tyugashev TE et al.
The Journal of Physical Chemistry. B, 2019
Structural Features of the Interaction between Human 8-Oxoguanine DNA Glycosylase hOGG1 and DNA.
Koval VV et al.
Acta Naturae, 2014
Step-by-step mechanism of DNA damage recognition by human 8-oxoguanine DNA glycosylase.
Kuznetsova AA et al.
Biochimica Et Biophysica Acta, 2014
DNA damage processing by human 8-oxoguanine-DNA glycosylase mutants with the occluded active site.
Lukina MV et al.
The Journal of Biological Chemistry, 2013
First evidence for digenic inheritance in hereditary colorectal cancer by mutations in the base excision repair genes.
Morak M et al.
European Journal of Cancer (oxford, England : 1990), 2011
Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
Radom CT et al.
The Journal of Biological Chemistry, 2007
Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.
Banerjee A et al.
Nature, 2005
Stimulation of DNA glycosylase activity of OGG1 by NEIL1: functional collaboration between two human DNA glycosylases.
Mokkapati SK et al.
Biochemistry, 2004
Electronic microarray technique for detection of nine base substitutions including single-nucleotide polymorphisms in the human OGG1 gene.
Gong Z et al.
Clinical Chemistry, 2004
The C-terminal alphaO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial beta-Ogg1 lacks this domain and does not have glycosylase activity.
Hashiguchi K et al.
Nucleic Acids Research, 2004
Product-assisted catalysis in base-excision DNA repair.
Fromme JC et al.
Nature Structural Biology, 2003
Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase.
Norman DP et al.
Biochemistry, 2003
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA.
Bruner SD et al.
Nature, 2000
Catalytic and DNA binding properties of the ogg1 protein of Saccharomyces cerevisiae: comparison between the wild type and the K241R and K241Q active-site mutant proteins.
Guibourt N et al.
Biochemistry, 2000
The critical active-site amine of the human 8-oxoguanine DNA glycosylase, hOgg1: direct identification, ablation and chemical reconstitution.
Nash HM et al.
Chemistry & Biology, 1997
A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer.
Lu R et al.
Current Biology : Cb, 1997
Molecular dynamics approach to identification of new OGG1 cancer-associated somatic variants with impaired activity.
Popov AV et al.
The Journal of Biological Chemistry, 0