Varaico: Literature-Extracted Genetic Variants

Gene:OGG1
Variant:p.D268N
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OGG1

NM_002542.6:p.D268N

Associated Papers

SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner.

Geng A et al.

Nucleic Acids Research, 2024

Roles of Active-Site Amino Acid Residues in Specific Recognition of DNA Lesions by Human 8-Oxoguanine-DNA Glycosylase (OGG1).

Tyugashev TE et al.

The Journal of Physical Chemistry. B, 2019

Structural Features of the Interaction between Human 8-Oxoguanine DNA Glycosylase hOGG1 and DNA.

Koval VV et al.

Acta Naturae, 2014

Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.

Radom CT et al.

The Journal of Biological Chemistry, 2007

Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase.

Norman DP et al.

Biochemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."