Varaico: Literature-Extracted Genetic Variants

Gene:OGG1
Variant:p.R304W
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OGG1

NM_002542.6:p.R304W

Associated Papers

Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians.

Yadav S et al.

Oncogene, 2020

32300177 (PubMed )
Supplement: 41388_2020_1280_MOESM3_ESM.xlsx › Main_Sheet_

Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes.

Tanisawa K et al.

Bmc Genomics, 2013

A novel R229Q OGG1 polymorphism results in a thermolabile enzyme that sensitizes KG-1 leukemia cells to DNA damaging agents.

Hill JW et al.

Cancer Detection and Prevention, 2007

Spontaneous loss-of-function mutations of the 8-oxoguanine DNA glycosylase gene in mice and exploration of the possible implication of the gene in senescence.

Mori M et al.

Free Radical Biology & Medicine, 2001

Novel human HALR (MLL3) gene encodes a protein homologous to ALR and to ALL-1 involved in leukemia, and maps to chromosome 7q36 associated with leukemia and developmental defects.

Tan YC et al.

Cancer Detection and Prevention, 2001

Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA.

Bruner SD et al.

Nature, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."