Associated Papers
Targeting base excision repair in precision oncology.
Montaldo NP et al.
Dna Repair, 2025
Defective DNA repair: a putative nexus linking immunological diseases, neurodegenerative disorders, and cancer.
Andarawi S et al.
Mutagenesis, 2025
Comprehensive Genomic Profiling Alters Clinical Diagnoses in a Significant Fraction of Tumors Suspicious of Sarcoma.
Öfverholm I et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2024
Correction: Candidate variants in DNA replication and repair genes in early-onset renal cell carcinoma patients referred for germline testing.
Demidova EV et al.
Bmc Genomics, 2023
Candidate variants in DNA replication and repair genes in early-onset renal cell carcinoma patients referred for germline testing.
Demidova EV et al.
Bmc Genomics, 2023
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells.
Robinson PS et al.
Nature Communications, 2022
Substitution mutational signatures in whole-genome-sequenced cancers in the UK population.
Degasperi A et al.
Science (new York, N.y.), 2022
Over-Mutated Mitochondrial, Lysosomal and TFEB-Regulated Genes in Parkinson's Disease.
Segur-Bailach E et al.
Journal of Clinical Medicine, 2022
Exome sequencing of familial adenomatous polyposis-like individuals identifies both known and novel causative genes.
Xavier A et al.
Clinical Genetics, 2021
Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma.
van den Boogaard ML et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021
Relationship between MUTYH, OGG1 and BRCA1 mutations and mRNA expression in breast and ovarian cancer predisposition.
Moscatello C et al.
Molecular and Clinical Oncology, 2021
Dominantly Inherited Hereditary Nonpolyposis Colorectal Cancer Not Caused by MMR Genes.
Terradas M et al.
Journal of Clinical Medicine, 2020
Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases in Colorectal Cancer Patients.
Vodicka P et al.
International Journal of Molecular Sciences, 2020
Contribution to colonic polyposis of recently proposed predisposing genes and assessment of the prevalence of NTHL1- and MSH3-associated polyposes.
Terradas M et al.
Human Mutation, 2019
Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer.
Leong TL et al.
Oncogene, 2019
Somatic APC mosaicism and oligogenic inheritance in genetically unsolved colorectal adenomatous polyposis patients.
Ciavarella M et al.
European Journal of Human Genetics : Ejhg, 2018
Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes.
DeRycke MS et al.
Molecular Genetics & Genomic Medicine, 2017
A systematic review and meta-analysis of the association between OGG1 Ser326Cys polymorphism and cancers.
Zhou PT et al.
Medical Oncology (northwood, London, England), 2015
Genetic association between hOGG1 C8069G polymorphism and colorectal cancer risk.
Sun X et al.
International Journal of Clinical and Experimental Medicine, 2015
Assessment of the association between hOGG1 C8069G polymorphism and colorectal cancer.
Lu M et al.
Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014
Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis.
Smith CG et al.
Journal of the National Cancer Institute, 2013
Abstracts of InSiGHT 5th Biennial Meeting. Pedigree, familial aspects of cancer and the Human Variome Project in conjunction with the COSA Familial Cancer Group. August 28-31, 2013.
Unknown Author
Familial Cancer, 2013
Meta-analysis demonstrates lack of association of the hOGG1 Ser326Cys polymorphism with bladder cancer risk.
Zhong DY et al.
Genetics and Molecular Research : Gmr, 2012
Variation in base excision repair capacity.
Wilson DM et al.
Mutation Research, 2011
8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes.
Janik J et al.
Mutation Research, 2011
First evidence for digenic inheritance in hereditary colorectal cancer by mutations in the base excision repair genes.
Morak M et al.
European Journal of Cancer (oxford, England : 1990), 2011
Analysis of the oxidative damage repair genes NUDT1, OGG1, and MUTYH in patients from mismatch repair proficient HNPCC families (MSS-HNPCC).
Garre P et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011
Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase.
Sidorenko VS et al.
The Febs Journal, 2009
Is base excision repair a tumor suppressor mechanism?
Sweasy JB et al.
Cell Cycle (georgetown, Tex.), 2006
Oxidized guanine lesions and hOgg1 activity in lung cancer.
Mambo E et al.
Oncogene, 2005
Polymorphic variation in hOGG1 and risk of cancer: a review of the functional and epidemiologic literature.
Weiss JM et al.
Molecular Carcinogenesis, 2005
Electronic microarray technique for detection of nine base substitutions including single-nucleotide polymorphisms in the human OGG1 gene.
Gong Z et al.
Clinical Chemistry, 2004
Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.
Halford SE et al.
The American Journal of Pathology, 2003
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA.
Bruner SD et al.
Nature, 2000
Frequent allelic loss at chromosome 3p distinct from genetic alterations of the 8-oxoguanine DNA glycosylase 1 gene in head and neck cancer.
Blons H et al.
Molecular Carcinogenesis, 1999