Varaico: Literature-Extracted Genetic Variants

Gene:OGG1
Variant:p.S326C
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OGG1

NM_002542.6:p.S326C

Associated Papers

A monofunctional-like mutant of DNA glycosylase NTHL1 changes the dynamics of DNA repair during acute oxidative stress.

Haslam J et al.

The Journal of Biological Chemistry, 2026

OGG1 and MUTYH DNA Glycosylases, the Dynamic Duo Against 8-Oxoguanine DNA Lesion: Structure, Regulation, and Novel Emerging Roles.

Gómez-Ramírez AP et al.

Biomolecules, 2026

DNA Damage and Repair in Thyroid Physiology and Disease.

Arczewska KD et al.

Endocrine Reviews, 2026

Impact of pesticide exposure on base excision repair gene polymorphisms in the Haryana population.

Gulia H et al.

Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals, 2025

Molecular Mechanisms of Preventable Causes of Oral Cancer and Precancer Through Polymorphism in DNA Base Excision Repair Genes in Patients with Tobacco Products Habits.

Sundaram E et al.

Journal of Maxillofacial and Oral Surgery, 2025

The OGG1 Ser326Cys polymorphism: molecular mechanisms of disease susceptibility and precision medicine applications.

Wang X et al.

Clinical Epigenetics, 2025

Oxidative DNA damage and DNA repair gene variants in differentiated thyroid cancer patients treated with radioactive iodine.

Avsar FN et al.

Endocrine, 2025

Molecular Duality of OGG1: From Genomic Guardian to Redox-Sensitive Modulator in Diseases.

Zhong R et al.

Antioxidants (basel, Switzerland), 2025

OGG1 augments the transcriptional activation of Foxp3 to promote iTreg differentiation for IBD alleviation.

Tian M et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025

Genetic Polymorphisms in Base Excision Repair (BER) and Nucleotide Excision Repair (NER) Pathways as Potential Biomarkers for Gynecological Cancers: A Comprehensive Literature Review.

Szatkowska M et al.

Cancers, 2025

OGG1S326C variant frequent in human populations facilitates inflammatory responses due to its extended interaction with DNA substrate.

Han J et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025

Integrative Computational Analysis of Common EXO5 Haplotypes: Impact on Protein Dynamics, Genome Stability, and Cancer Progression.

Mazza F et al.

Journal of Chemical Information and Modeling, 2025

40115981 (PubMed )
Supplement: ci5c00067_si_002.xlsx › scored_ALL_haplotypes_1MAF_cano

APEX1 Polymorphisms Affect Acute Myeloid Leukemia Risk, and Its Expression Is Involved in Cell Proliferation and Differentiation.

Gotoh N et al.

International Journal of Laboratory Hematology, 2025

Defective DNA repair: a putative nexus linking immunological diseases, neurodegenerative disorders, and cancer.

Andarawi S et al.

Mutagenesis, 2025

Genomic instability in ovarian cancer: Through the lens of single nucleotide polymorphisms.

Canchi Sistla H et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2025

Targeting the 8-oxodG Base Excision Repair Pathway for Cancer Therapy.

Piscone A et al.

Cells, 2025

A systematic review and functional in-silico analysis of genes and variants associated with amyotrophic lateral sclerosis.

Arreola-Aldape CA et al.

Frontiers in Neuroscience, 2025

40589786 (PubMed )
Supplement: Table_3.xlsx › Sheet1

The Human 8-oxoG DNA Glycosylase 1 (OGG1) Ser326Cys Polymorphism in Infertile Men.

González-Díaz CA et al.

Biomedicines, 2024

Investigating Tobacco's Impact on DNA Repair Genes and Risks in Oral Precancer and Cancer: A Comprehensive Research Study.

Mohammad S et al.

Journal of Maxillofacial and Oral Surgery, 2024

Polymorphic variants of the hOGG1, APEX1, XPD, SOD2, and CAT genes involved in DNA repair processes and antioxidant defense and their association with breast cancer risk.

Timofeeva АА et al.

Vavilovskii Zhurnal Genetiki I Selektsii, 2024

Influence of genetic polymorphisms of Hg metabolism and DNA repair on the frequencies of micronuclei, nucleoplasmic bridges, and nuclear buds in communities living in gold mining areas.

Espitia-Pérez L et al.

Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 2024

Polymorphisms of DNA Repair Genes in Thyroid Cancer.

Gielecińska A et al.

International Journal of Molecular Sciences, 2024

Genetic variations in DNA excision repair pathway contribute to the chemosensitivity and prognosis of acute myeloid leukemia.

Zhang A et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2024

Genetic Associations of Primary Angle-Closure Disease: A Systematic Review and Meta-Analysis.

Liang YJ et al.

Jama Ophthalmology, 2024

Are changes in olanzapine-induced liver enzyme levels associated with GSTT1, GSTM1, GSTP1, and OGG1 gene polymorphisms?

Elkama A et al.

Arhiv Za Higijenu Rada I Toksikologiju, 2024

Modulation of gene expression and influence of gene polymorphisms related to genotoxicity and redox status on occupational exposure to inhaled anesthetics.

Silva MAP et al.

International Journal of Hygiene and Environmental Health, 2024

Association between polymorphisms of the DNA repair genes RAD51 and OGG1 and risk of cardiovascular disease.

Alomair A et al.

Molecular Medicine Reports, 2024

Genetic and epigenetic alterations in DNA repair genes and treatment outcome of chemoradiotherapy in cervical cancer.

Kushwah AS et al.

Critical Reviews in Oncology/hematology, 2024

Decreased DNA repair capacity caused by exposure to metal mixtures is modulated by the PARP1 rs1136410 variant in newborns from a polluted metropolitan area.

Paz-Sabillón M et al.

Environmental Research, 2024

XRCC1 and hOGG1 polymorphisms and endometrial carcinoma: A meta-analysis.

He S et al.

Open Medicine (warsaw, Poland), 2024

Genetic polymorphisms and platinum-induced hematological toxicity: a systematic review.

Zheng Y et al.

Frontiers in Pharmacology, 2024

Quantitative assessment of the association between TNF-α gene polymorphisms and angina risk.

Xu S et al.

American Journal of Translational Research, 2024

The Incidence of the XRCC1 rs25487 and PON1 rs662 Polymorphisms in a Population from Central Brazil: Patterns in an Area with a High Level of Agricultural Activity.

Alves AA et al.

Biochemical Genetics, 2023

Understanding DNA Damage Response and DNA Repair in Multiple Myeloma.

Petrilla C et al.

Cancers, 2023

Single-Nucleotide Polymorphisms in Base-Excision Repair-Related Genes Involved in the Risk of an Occurrence of Non-Alcoholic Fatty Liver Disease.

Ziółkowska S et al.

International Journal of Molecular Sciences, 2023

Genetic variants in varicocele-related male infertility: a systematic review and future directions.

Mostafa T et al.

Human Fertility (cambridge, England), 2023

The ADORA2A TT Genotype Is Associated with Anti-Inflammatory Effects of Caffeine in Response to Resistance Exercise and Habitual Coffee Intake.

Rahimi MR et al.

Nutrients, 2023

Strong Cumulative Evidence of Associations of 6 Single Nucleotide Polymorphisms with Ovarian Cancer Risk: An Umbrella Review.

Huo YJ et al.

Journal of Clinical Medicine, 2023

Next-generation sequencing of prolidase gene identifies novel and common variants associated with low prolidase in coronary artery ectasia.

Pekkoc-Uyanik KC et al.

Molecular Biology Reports, 2023

Neural Tube Defects and Folate Deficiency: Is DNA Repair Defective?

Wang X et al.

International Journal of Molecular Sciences, 2023

The interplay between XPG-Asp1104His polymorphism and reproductive risk factors elevates risk of breast cancer in Tanzanian women: A multiple interaction analysis.

Adolf IC et al.

Cancer Medicine, 2023

Association of buccal micronucleus cytome assay (BMNCyt) biomarkers with inorganic element concentration and genetic polymorphisms in welders.

Quintana-Sosa M et al.

Environmental Toxicology and Pharmacology, 2023

Association of MTHFR C667T Polymorphism, Homocysteine, and B Vitamins with Senile Cataract.

Luo J et al.

Journal of Nutritional Science and Vitaminology, 2023

Complex Roles of NEIL1 and OGG1: Insights Gained from Murine Knockouts and Human Polymorphic Variants.

Lloyd RS

Dna, 2022

hOGG1 rs1052133 Polymorphism and Prostate Cancer Risk: A Chinese Case-Control Study and Meta-Analysis.

Xu H et al.

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 2022

Genetic susceptibility of bladder cancer in the Lebanese population.

Kourie HR et al.

Bmc Medical Genomics, 2022

36253817 (PubMed )
Supplement: 12920_2022_1372_MOESM1_ESM.xlsx › sheet_1
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