Varaico: Literature-Extracted Genetic Variants

Gene:OLR1
Variant:p.K167N
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OLR1

NM_002543.4:p.K167N

Associated Papers

Moroccan genome project: genomic insight into a North African population.

El Fahime E et al.

Communications Biology, 2025

Computational analysis of congenital heart disease associated SNPs: unveiling their impact on the gene regulatory system.

Vashisht S et al.

Bmc Genomics, 2025

39838281 (PubMed )
Supplement: 12864_2025_11232_MOESM4_ESM.xlsx › ClinVar_CHD-SNPs_uniq

Recurrent somatic mutations of FAT family cadherins induce an aggressive phenotype and poor prognosis in anaplastic large cell lymphoma.

Villa M et al.

British Journal of Cancer, 2024

39478125 (PubMed )
Supplement: 41416_2024_2881_MOESM1_ESM.pdf

LOX-1 variants modulate the severity of cardiovascular disease: state of the art and future directions.

Lubrano V et al.

Molecular and Cellular Biochemistry, 2024

Genetic regulatory effects in response to a high-cholesterol, high-fat diet in baboons.

Lin W et al.

Cell Genomics, 2024

Genetic regulatory effects in response to a high cholesterol, high fat diet in baboons.

Lin W et al.

Biorxiv : the Preprint Server for Biology, 2023

Biochemical Characteristics of iPSC-Derived Dopaminergic Neurons from N370S GBA Variant Carriers with and without Parkinson's Disease.

Grigor'eva EV et al.

International Journal of Molecular Sciences, 2023

36901867 (PubMed )
Supplement: ijms-24-04437-s001.zip › ijms-2163006-supplementary.pdf

Genetic variations in OLR1 gene associated with PCOS and atherosclerotic risk factors.

Sahin SB et al.

Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research, 2023

Discovering Genotype Variants in an Infant with VACTERL through Clinical Exome Sequencing: A Support for Personalized Risk Assessment and Disease Prevention.

Pelizzo G et al.

Pediatric Reports, 2021

Lipoprotein receptor signalling in atherosclerosis.

Mineo C

Cardiovascular Research, 2020

Introducing the first whole genomes of nationals from the United Arab Emirates.

AlSafar HS et al.

Scientific Reports, 2019

31604968 (PubMed )
Supplement: 41598_2019_50876_MOESM1_ESM.xlsx › UAE_S002

HDAC9 Polymorphisms Predict Susceptibility, Severity, and Short-Term Outcome of Large Artery Atherosclerotic Stroke in Chinese Population.

Wang M et al.

Journal of Molecular Neuroscience : Mn, 2019

Genetic analysis of early onset familial coronary artery diseases.

Ghorbani MJ et al.

Archives of Medical Sciences. Atherosclerotic Diseases, 2019

Predicting cardiovascular disease in familial hypercholesterolemia.

Paquette M et al.

Current Opinion in Lipidology, 2018

Are IVS4 SNPs of OLR1 gene associated with coronary artery disease: Is there a linkage between IVS4 SNPs?

Kurnaz-Gomleksiz O et al.

Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University, 2018

Molecular genetic studies in Saudi population; identified variants from GWAS and meta-analysis in stroke.

Alharbi KK et al.

Saudi Journal of Biological Sciences, 2018

Scavenger Receptor LOX1 Genotype Predicts Coronary Artery Disease in Patients With Familial Hypercholesterolemia.

Paquette M et al.

The Canadian Journal of Cardiology, 2017

Association of the LOX-1 rs1050283 Polymorphism with Risk for Atherosclerotic Cerebral Infarction and its Effect on sLOX-1 and LOX-1 Expression in a Chinese Population.

Guo X et al.

Journal of Atherosclerosis and Thrombosis, 2017

LOX-1 gene variants and maternal levels of plasma oxidized LDL and malondialdehyde in patients with gestational diabetes mellitus.

Aydemir B et al.

Archives of Gynecology and Obstetrics, 2016

The Influence of OLR1 and PCSK9 Gene Polymorphisms on Ischemic Stroke: Evidence from a Meta-Analysis.

Au A et al.

Scientific Reports, 2015

The association of lectin-like oxidized LDL receptor 1 (LOX-1) K167N and 3'UTR188CT polymorphisms with maternal plasma soluble LOX-1 levels and preeclampsia risk in Turkish population.

Tuten A et al.

Archives of Gynecology and Obstetrics, 2015

Associations between Lectin-like, oxidized low-density lipoprotein receptor-1 G501C and 3'-UTR-C188T polymorphisms with coronary artery disease: a meta-analysis.

Feng TY et al.

International Journal of Clinical and Experimental Medicine, 2015

The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.

Tang X et al.

Nucleic Acids Research, 2014

25352556 (PubMed )
Supplement: supp_gku1005_nar-01266-met-n-2014-File012.xlsx › TCGA-A2-A0ER-01A.domain

Association of LOX-1 gene polymorphisms with cerebral infarction in northern Chinese Han population.

Liu X et al.

Lipids in Health and Disease, 2014

The gene polymorphism of LOX1 predicts the incidence of LVH in patients with essential hypertension.

Xu X et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2014

Whole exome sequencing identifies novel genes for fetal hemoglobin response to hydroxyurea in children with sickle cell anemia.

Sheehan VA et al.

Plos One, 2014

High density lipoprotein cholesterol levels are an independent predictor of the progression of chronic kidney disease.

Baragetti A et al.

Journal of Internal Medicine, 2013

Genetic polymorphisms and the risk of myocardial infarction in patients under 45 years of age.

Sakowicz A et al.

Biochemical Genetics, 2013

The role of OLR1 polymorphisms in determining the risk and prognosis of ischemic stroke in a Chinese population.

Zhang J et al.

Neurorehabilitation, 2013

The LOX-1 3'UTR188CT polymorphism and coronary artery disease in Turkish patients.

Kurnaz O et al.

Molecular Biology Reports, 2012

Association between OLR1 K167N SNP and intima media thickness of the common carotid artery in the general population.

Predazzi IM et al.

Plos One, 2012

G501C polymorphism of the oxidized LDL receptor gene is associated with albuminuria in Chinese essential hypertension patients.

Hou XW et al.

Genetics and Molecular Research : Gmr, 2011

LOX-1/LOXIN: the yin/yang of atheroscleorosis.

Mango R et al.

Cardiovascular Drugs and Therapy, 2011

A candidate gene study revealed sex-specific association between the OLR1 gene and carotid plaque.

Wang L et al.

Stroke, 2011

Associations between oxidized-lipoprotein receptor 1 G501C and 3'-UTR-C188T polymorphisms and coronary artery disease: a meta-analysis.

Cheng Y et al.

Cardiology, 2011

Genetic variability and the risk of myocardial infarction in Poles under 45 years of age.

Sakowicz A et al.

Archives of Medical Science : Ams, 2010

The G501C polymorphism of the oxidized low-density lipoprotein-receptor 1 gene is associated with acute coronary syndrome in the Han Chinese population.

Wang Y et al.

Dna and Cell Biology, 2010

Functional analysis and molecular dynamics simulation of LOX-1 K167N polymorphism reveal alteration of receptor activity.

Biocca S et al.

Plos One, 2009

Candidate gene polymorphisms and the 9p21 locus in acute coronary syndromes.

Tousoulis D et al.

Trends in Molecular Medicine, 2008

Variation in the human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) gene is associated with plasma soluble LOX-1 levels.

Brinkley TE et al.

Experimental Physiology, 2008

Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD.

Knowles JW et al.

Bmc Medical Genetics, 2008

The G501C polymorphism of oxidized LDL receptor gene [OLR-1] is associated with susceptibility and serum C-reactive protein concentration in Chinese essential hypertensives.

Hou XW et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2008

[Association of APOA5 gene polymorphism with levels of lipids and atherosclerotic cerebral infarction in Chinese].

Li J et al.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics, 2007

Lectin-like oxidized-LDL receptor-1 (LOX-1) polymorphisms influence cardiovascular events rate during statin treatment.

Puccetti L et al.

International Journal of Cardiology, 2007

Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study.

Morgan TM et al.

Jama, 2007

G501C polymorphism of oxidized LDL receptor gene (OLR1) and ischemic stroke.

Hattori H et al.

Brain Research, 2006

Genetic factors for obesity.

Yamada Y et al.

International Journal of Molecular Medicine, 2006

Assessment of genetic factors for type 2 diabetes mellitus.

Yamada Y et al.

International Journal of Molecular Medicine, 2006

The 3'-UTR C>T polymorphism of the oxidized LDL-receptor 1 (OLR1) gene does not associate with coronary artery disease in Italian CAD patients or with the severity of coronary disease.

Sentinelli F et al.

Nutrition, Metabolism, and Cardiovascular Diseases : Nmcd, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."