Associated Papers
OPA1 deficiency accelerates hippocampal synaptic remodelling and age-related deficits in learning and memory.
Bevan RJ et al.
Brain Communications, 2020
A randomized, placebo-controlled trial of the benzoquinone idebenone in a mouse model of OPA1-related dominant optic atrophy reveals a limited therapeutic effect on retinal ganglion cell dendropathy and visual function.
Smith TG et al.
Neuroscience, 2016
Specific deficits in visual electrophysiology in a mouse model of dominant optic atrophy.
Barnard AR et al.
Experimental Eye Research, 2011
Electrophysiological and histologic assessment of retinal ganglion cell fate in a mouse model for OPA1-associated autosomal dominant optic atrophy.
Heiduschka P et al.
Investigative Ophthalmology & Visual Science, 2010
OPA1-associated disorders: phenotypes and pathophysiology.
Amati-Bonneau P et al.
The International Journal of Biochemistry & Cell Biology, 2009
Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function.
Davies VJ et al.
Human Molecular Genetics, 2007
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