Associated Papers
Structural modelling and mutation analysis of a nociceptin receptor and its ligand complexes.
Akuzawa N et al.
Journal of Biochemistry, 2007
Bremazocine recognizes the difference in four amino acid residues to discriminate between a nociceptin/orphanin FQ receptor and opioid receptors.
Seki T et al.
Japanese Journal of Pharmacology, 1998
Replacement of Gln280 by His in TM6 of the human ORL1 receptor increases affinity but reduces intrinsic activity of opioids.
Mollereau C et al.
Febs Letters, 1996
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