Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.A6V
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OPRM1

NM_000914.5:p.A6V

Associated Papers

Haplotype-based Analysis of 6q24-25 for Association with Rheumatoid Arthritis.

Gauri LA et al.

The Journal of the Association of Physicians of India, 2024

OPRM1 Gene Polymorphism in Women with Alcohol Use Disorder.

Boroń A et al.

International Journal of Molecular Sciences, 2024

Opioid Receptor Mu 1 Gene (OPRM1) A118G Polymorphism and Emotional Modulation of Pain.

Trimble EA et al.

Journal of Pain Research, 2024

OPRM1 and BDNF polymorphisms associated with a compensatory neurophysiologic signature in knee osteoarthritis patients.

Gonçalves FT et al.

Neurophysiologie Clinique = Clinical Neurophysiology, 2023

Association between opioid and dopamine receptor gene polymorphisms OPRM1 rs1799971, DAT VNTR 9-10 repeat allele, DRD1 rs4532 and DRD2 rs1799732 and alcohol dependence: an ethnicity oriented meta-analysis.

Suresh N et al.

Pharmacogenetics and Genomics, 2023

Pharmacogenomic profile of actionable molecular variants related to drugs commonly used in anesthesia: WES analysis reveals new mutations.

Parada-Márquez JF et al.

Frontiers in Pharmacology, 2023

37021041 (PubMed )
Supplement: Table3.xlsx › Hoja1

The Influence of OPRM1 A118G Polymorphism on the Dosage of Morphine in Patients with Advanced Liver Cancer.

Cheng H et al.

Journal of the College of Physicians and Surgeons--pakistan : Jcpsp, 2021

Opioid Addiction and Opioid Receptor Dimerization: Structural Modeling of the OPRD1 and OPRM1 Heterodimer and Its Signaling Pathways.

Wu B et al.

International Journal of Molecular Sciences, 2021

Population-specific genetic background for the OPRM1 variant rs1799971 (118A>G): implications for genomic medicine and functional analysis.

Levran O et al.

Molecular Psychiatry, 2021

Deleterious variants in genes regulating mammalian reproduction in Neanderthals, Denisovans and extant humans.

Greer C et al.

Human Reproduction (oxford, England), 2021

33417716 (PubMed )
Supplement: deaa347_supplementary_data.zip › Suppl_Table_SV_Neand_Shared_Extinct_Revised.pdf

Overview of Genetic Analysis of Human Opioid Receptors.

Spampinato SM

Methods in Molecular Biology (clifton, N.j.), 2021

The μ-opioid receptor gene A118G polymorphism is associated with insecure attachment in children with disruptive mood regulation disorder and their mothers.

Cimino S et al.

Brain and Behavior, 2020

Neuropharmacological and Neurogenetic Correlates of Opioid Use Disorder (OUD) As a Function of Ethnicity: Relevance to Precision Addiction Medicine.

Abijo T et al.

Current Neuropharmacology, 2020

Implication of OPRM1 A118G Polymorphism in Opioids Addicts in Pakistan: In vitro and In silico Analysis.

Ahmed M et al.

Journal of Molecular Neuroscience : Mn, 2018

Convergent Balancing Selection on the Mu-Opioid Receptor in Primates.

Sweeney CG et al.

Molecular Biology and Evolution, 2017

Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver Injury.

Randesi M et al.

Cellular and Molecular Gastroenterology and Hepatology, 2017

An Expert Review of Pharmacogenomics of Sickle Cell Disease Therapeutics: Not Yet Ready for Global Precision Medicine.

Mnika K et al.

Omics : a Journal of Integrative Biology, 2016

COMT and OPRM1 Genotype Associations with Daily Knee Pain Variability and Activity Induced Pain.

Martire LM et al.

Scandinavian Journal of Pain, 2016

[μ-Opioid Receptor Gene (OPRM1) Polymorphisms A118G and C17T in Alcohol Dependence: A Turkish Sample].

Gürel ŞC et al.

Turk Psikiyatri Dergisi = Turkish Journal of Psychiatry, 2016

A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioids in vitro.

Knapman A et al.

British Journal of Pharmacology, 2015

Human population genetic structure detected by pain-related mu opioid receptor gene polymorphisms.

López Soto EJ et al.

Genetics and Molecular Biology, 2015

Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1).

Knapman A et al.

British Journal of Pharmacology, 2015

Genetic Addiction Risk Score (GARS): molecular neurogenetic evidence for predisposition to Reward Deficiency Syndrome (RDS).

Blum K et al.

Molecular Neurobiology, 2014

Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants.

Wang S et al.

Molecular Neurobiology, 2014

Mu opioid receptor gene: new point mutations in opioid addicts.

Dinarvand A et al.

Basic and Clinical Neuroscience, 2014

Large-scale polymorphism discovery in macaque G-protein coupled receptors.

Goswami DB et al.

Bmc Genomics, 2013

The associations between OPRM 1 and COMT genotypes and postoperative pain, opioid use, and opioid-induced sedation.

Henker RA et al.

Biological Research for Nursing, 2013

Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.

Clarke TK et al.

Neuroscience Letters, 2013

Gene polymorphisms of OPRM1 A118G and ABCB1 C3435T may influence opioid requirements in Chinese patients with cancer pain.

Gong XD et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2013

Gender-stratified gene and gene-treatment interactions in smoking cessation.

Lee W et al.

The Pharmacogenomics Journal, 2012

21808284 (PubMed )
Supplement: NIHMS305090-supplement-3.pdf

Association of polymorphisms of the mu opioid receptor gene with the severity of HIV infection and response to HIV treatment.

Proudnikov D et al.

The Journal of Infectious Diseases, 2012

The genetics of the opioid system and specific drug addictions.

Levran O et al.

Human Genetics, 2012

Human mu-opioid receptor gene A118G polymorphism predicts the efficacy of tramadol/acetaminophen combination tablets (ultracet) in oxaliplatin-induced painful neuropathy.

Liu YC et al.

Cancer, 2012

The role of the Asn40Asp polymorphism of the mu opioid receptor gene (OPRM1) on alcoholism etiology and treatment: a critical review.

Ray LA et al.

Alcoholism, Clinical and Experimental Research, 2012

A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women.

Crystal HA et al.

Addiction Biology, 2012

Genetic variability of pain perception and treatment--clinical pharmacological implications.

Lötsch J

European Journal of Clinical Pharmacology, 2011

The μ-opioid receptor variant N190K is unresponsive to peptide agonists yet can be rescued by small-molecule drugs.

Fortin JP et al.

Molecular Pharmacology, 2010

OPRM1 SNP (A118G): involvement in disease development, treatment response, and animal models.

Mague SD et al.

Drug and Alcohol Dependence, 2010

Single-nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu-opioid receptor and may contribute to the genetic risk for addiction.

Deb I et al.

Journal of Neurochemistry, 2010

Identification of single nucleotide polymorphisms within exon 1 of the canine mu-opioid receptor gene.

Hawley AT et al.

Veterinary Anaesthesia and Analgesia, 2010

A micro opioid receptor gene polymorphism (A118G) and naltrexone treatment response in adherent Korean alcohol-dependent patients.

Kim SG et al.

Psychopharmacology, 2009

Genomics of complex disorders I.

Unknown Author

Genomic Medicine, 2008

G protein-coupled receptor pharmacogenetics.

Thompson MD et al.

Methods in Molecular Biology (clifton, N.j.), 2008

A118g polymorphism in mu opioid receptor gene (oprm1): association with opiate addiction in subjects of Indian origin.

Kapur S et al.

Journal of Integrative Neuroscience, 2007

The opioid system in alcohol and drug dependence: family-based association study.

Xuei X et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2007

Correlation of circulatory immunoglobulin levels with Mu opiate receptor allele.

Sharad S et al.

Indian Journal of Biochemistry & Biophysics, 2007

Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence.

Zhang H et al.

Human Molecular Genetics, 2006

[Are polymorphisms in the mu-opioid receptor important for opioid therapy?].

Lötsch J et al.

Schmerz (berlin, Germany), 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."