Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.T8T
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OPRM1

NM_000914.5:p.T8T

Associated Papers

COMT and OPRM1 Genotype Associations with Daily Knee Pain Variability and Activity Induced Pain.

Martire LM et al.

Scandinavian Journal of Pain, 2016

The associations between OPRM 1 and COMT genotypes and postoperative pain, opioid use, and opioid-induced sedation.

Henker RA et al.

Biological Research for Nursing, 2013

Single-nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu-opioid receptor and may contribute to the genetic risk for addiction.

Deb I et al.

Journal of Neurochemistry, 2010

Clinical response to morphine in cancer patients and genetic variation in candidate genes.

Ross JR et al.

The Pharmacogenomics Journal, 2005

Gene polymorphisms of the mu opioid receptor in methamphetamine abusers.

Ide S et al.

Annals of the New York Academy of Sciences, 2004

Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity?

Lötsch J et al.

Anesthesiology, 2002

Relationship of the delta-opioid receptor gene to heroin abuse in a large Chinese case/control sample.

Xu K et al.

American Journal of Medical Genetics, 2002

Bioinformatic analysis of the human mu opioid receptor (OPRM1) splice and polymorphic variants.

Xin L et al.

Aaps Pharmsci, 2002

Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction.

Bond C et al.

Proceedings of the National Academy of Sciences of the United States of America, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."