Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.N40D
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OPRM1

NM_000914.5:p.N40D

Associated Papers

Vitamin D Receptor (VDR) Polymorphisms and Cardiometabolic Profiles in Orthopedic Patients: A Cluster-Based Analysis.

Larysz D et al.

International Journal of Molecular Sciences, 2026

Genetic landscape of morphine response in BXD recombinant inbred mice.

Yin Q et al.

Hgg Advances, 2026

Pharmacogenomics and Opioid Efficacy in Sickle Cell Disease.

Elshaikh RH et al.

Medicina (kaunas, Lithuania), 2026

Associations Between Genetic Polymorphisms and Psychological Variables in Women With Fibromyalgia: A Cross-Sectional Study.

Riquelme-Aguado V et al.

European Journal of Pain (london, England), 2026

OPRM1 gene polymorphism linked to anxiety in cancer-related pain patients: an observational study.

Mo J et al.

Frontiers in Pain Research (lausanne, Switzerland), 2026

Genetic Influence on Extended-Release Naltrexone Treatment Outcomes in Patients with Opioid Use Disorder: An Exploratory Study.

Juya F et al.

Brain Sciences, 2025

The Mental Roots of Performance: A Preliminary Meta-Analysis of Cognitive Genes and Athlete Status.

İpekoğlu G et al.

Molecular Neurobiology, 2025

Whole-exome sequencing study of opioid dependence offers novel insights into the contributions of exome variants.

Wang L et al.

Translational Psychiatry, 2025

Genetic and Epigenetic Approaches to Opioid Use Disorder.

Ranadeva ND et al.

Expert Reviews in Molecular Medicine, 2025

Association of catechol-O-methyltransferase genetic polymorphism with neuromodulation treatment response in women with fecal or urinary incontinence.

Florian-Rodriguez ME et al.

American Journal of Obstetrics and Gynecology, 2025

Spatial transcriptomics reveals distinct cell type dynamics following opioid dependence in mice with the common human variant in the μ-opioid receptor, Oprm1 A118G.

Xie Y et al.

Research Square, 2025

The Role of Pharmacogenetic Biomarkers in Pain.

Martin da Silva I et al.

Biomedicines, 2025

Effect of pain-related sodium channels SCN9A and SCN10A polymorphisms in migraine chronification.

Kilic E et al.

Neurological Research, 2025

Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort.

Åkerlund M et al.

Pain, 2025

ABCB1, SLC22A1, COMT, and OPRM1 genotypes: Study of their influence on plasma methadone levels and clinical response to methadone maintenance treatment in opioid use disorder.

Ait Tayeb AEK et al.

Fundamental & Clinical Pharmacology, 2025

Association of CYP2B6 and OPRM1 Genotypes with Methadone Dose Requirements and Serum Concentrations in a Vietnamese Cohorts.

Nguyen QG et al.

Balkan Journal of Medical Genetics : Bjmg, 2025

Association of Genetic Variants, Such as the μ-Opioid Receptor 1 (OPRM1) rs1799971 and Catechol-O-Methyltransferase (COMT) rs4680, with Phenotypic Expression of Fibromyalgia.

Erenas Ondategui I et al.

Biomedicines, 2025

Knowledge of the genetics of human pain gained over the last decade from next-generation sequencing.

Kringel D et al.

Pharmacological Research, 2025

Association of OPRM1 and OPRD1 Polymorphisms with Pain and Opioid Adverse Reactions in Colorectal Cancer.

Gutiérrez-Cáceres C et al.

Pharmaceuticals (basel, Switzerland), 2025

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc6.xlsx › Sheet1

FYN Tyrosine Kinase Gene Polymorphisms in Alcohol-Dependent Korean Patients.

Huh SY et al.

Alpha Psychiatry, 2025

The impact of genetic variability on Alzheimer's therapies: obstacles for pharmacogenetic progress.

Cacabelos R et al.

Expert Opinion on Drug Metabolism & Toxicology, 2025

Exploring the Pharmacogenomic Map of Croatia: PGx Clustering of 522-Patient Cohort Based on UMAP + HDBSCAN Algorithm.

Brlek P et al.

International Journal of Molecular Sciences, 2025

The Rise of Fentanyl: Molecular Aspects and Forensic Investigations.

Barletta C et al.

International Journal of Molecular Sciences, 2025

Correlation between gene polymorphisms and perioperative analgesia in patients undergoing gynecological surgery.

Cai M et al.

Frontiers in Genetics, 2025

Pharmacogenomics and genetic ancestry in Colombia: a study on all variant drug annotations of PharmGKB.

Acosta-Monterrosa AA et al.

Frontiers in Pharmacology, 2025

40949159 (PubMed )
Supplement: Table1.xlsx › Studies

Molecular genetic basis of the primary emotions in young adults: an exploratory analysis of genetic polymorphisms across dopamine, serotonin, oxytocin, endogenous opioid, and neurotrophic factor pathways.

Glavač T et al.

Frontiers in Pharmacology, 2025

OPRM1 A118G Polymorphism and Ondansetron Efficacy for Postoperative Nausea and Vomiting in Laparoscopic Gynaecological Surgery: A Retrospective Cohort Study.

Zhao X et al.

Therapeutics and Clinical Risk Management, 2025

Genomic factors associated with substance use disorder relapse: A critical review.

Al-Marzooqi N et al.

Addictive Behaviors Reports, 2024

Genetic Variants Linked to Opioid Addiction: A Genome-Wide Association Study.

Panday SK et al.

International Journal of Molecular Sciences, 2024

Pharmacogenotyping disproves genetic cause of drug-related problems in family history: a case report.

Bollinger A et al.

Bmc Anesthesiology, 2024

Scaled and efficient derivation of loss-of-function alleles in risk genes for neurodevelopmental and psychiatric disorders in human iPSCs.

Zhang H et al.

Stem Cell Reports, 2024

39270650 (PubMed )
Supplement: mmc2.pdf

Whole-exome sequencing study of opioid dependence offers novel insights into the contributions of exome variants.

Wang L et al.

Medrxiv : the Preprint Server for Health Sciences, 2024

Effect of A118G (rs1799971) single-nucleotide polymorphism of the μ-opioid receptor OPRM1 gene on intraoperative remifentanil requirements in Japanese women undergoing laparoscopic gynecological surgery.

Zou R et al.

Neuropsychopharmacology Reports, 2024

Influence of Clinical and Genetic Factors on Propofol Dose Requirements: A Genome-wide Association Study.

Ahlström S et al.

Anesthesiology, 2024

Genetic influence on treatment outcomes in patients with pain-related temporomandibular disorders.

Zlendić M et al.

Journal of Oral Rehabilitation, 2024

Functional differences in the mu opioid receptor SNP 118A>G are dependent on receptor splice-variant and agonist-specific recruitment of β-arrestin.

Patrick C et al.

Clinical and Translational Science, 2024

Haplotype-based Analysis of 6q24-25 for Association with Rheumatoid Arthritis.

Gauri LA et al.

The Journal of the Association of Physicians of India, 2024

Pharmacokinetic and neuroimmune pharmacogenetic impacts on slow-release morphine cancer pain control and adverse effects.

Barratt DT et al.

The Pharmacogenomics Journal, 2024

38824169 (PubMed )
Supplement: 41397_2024_339_MOESM3_ESM.pdf

Impacts of genetic polymorphisms and cancer cachexia on naldemedine pharmacokinetics and bowel movements in patients receiving opioid analgesics.

Nakatsugawa E et al.

Fundamental & Clinical Pharmacology, 2024

Association of the OPRM1 variant rs1799971 (A118G) and clinical manifestations in tramadol poisoned patients: a cross-sectional study.

Ershad A et al.

Clinical Toxicology (philadelphia, Pa.), 2024

A Pharmacogenomics-Based In Silico Investigation of Opioid Prescribing in Post-operative Spine Pain Management and Personalized Therapy.

Lewandrowski KU et al.

Cellular and Molecular Neurobiology, 2024

Association of OPRM1 rs1799971, HTR1B rs6296 and COMT rs4680 polymorphisms with clinical phenotype among women with fibromyalgia.

Fernández-de-Las-Peñas C et al.

Scientific Reports, 2024

Clinical prediction of opioid use disorder in chronic pain patients: a cohort-retrospective study with a pharmacogenetic approach.

Escorial M et al.

Minerva Anestesiologica, 2024

A systematic review and meta-analysis of the impacts of germline pharmacogenomics on severe toxicity and symptom burden in adult patients with cancer.

Lingaratnam S et al.

Clinical and Translational Science, 2024

Variation in the mu-opioid receptor gene (OPRM1) moderates the influence of maternal sensitivity on child attachment.

Tchalova K et al.

Translational Psychiatry, 2024

Pharmacogenetic Approaches in Personalized Medicine for Postoperative Pain Management.

Ferreira do Couto ML et al.

Biomedicines, 2024

SNP-based and haplotype-based genome-wide association on drug dependence in Han Chinese.

Xu H et al.

Bmc Genomics, 2024

OPRM1 Gene Polymorphism in Women with Alcohol Use Disorder.

Boroń A et al.

International Journal of Molecular Sciences, 2024

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."