Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.L85I
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OPRM1

NM_000914.5:p.L85I

Associated Papers

Novel variants of engineered water soluble mu opioid receptors with extensive mutations and removal of cysteines.

Xi J et al.

Proteins, 2021

A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioids in vitro.

Knapman A et al.

British Journal of Pharmacology, 2015

Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1).

Knapman A et al.

British Journal of Pharmacology, 2015

Morphine-induced internalization of the L83I mutant of the rat μ-opioid receptor.

Cooke AE et al.

British Journal of Pharmacology, 2015

Buprenorphine signalling is compromised at the N40D polymorphism of the human μ opioid receptor in vitro.

Knapman A et al.

British Journal of Pharmacology, 2014

Elucidation of mu-Opioid Gene Structure: How Genetics Can Help Predict Responses to Opioids.

Diatchenko L et al.

European Journal of Pain Supplements, 2011

Functional characterization of human variants of the mu-opioid receptor gene.

Ravindranathan A et al.

Proceedings of the National Academy of Sciences of the United States of America, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."