Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.N152D
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OPRM1

NM_000914.5:p.N152D

Associated Papers

Overview of Genetic Analysis of Human Opioid Receptors.

Spampinato SM

Methods in Molecular Biology (clifton, N.j.), 2021

Convergent Balancing Selection on the Mu-Opioid Receptor in Primates.

Sweeney CG et al.

Molecular Biology and Evolution, 2017

Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1).

Knapman A et al.

British Journal of Pharmacology, 2015

Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.

Clarke TK et al.

Neuroscience Letters, 2013

Association of polymorphisms of the mu opioid receptor gene with the severity of HIV infection and response to HIV treatment.

Proudnikov D et al.

The Journal of Infectious Diseases, 2012

G protein-coupled receptor pharmacogenetics.

Thompson MD et al.

Methods in Molecular Biology (clifton, N.j.), 2008

[Are polymorphisms in the mu-opioid receptor important for opioid therapy?].

Lötsch J et al.

Schmerz (berlin, Germany), 2005

COMBINE genetics study: the pharmacogenetics of alcoholism treatment response: genes and mechanisms.

Goldman D et al.

Journal of Studies on Alcohol. Supplement, 2005

Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor.

Beyer A et al.

Journal of Neurochemistry, 2004

Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity?

Lötsch J et al.

Anesthesiology, 2002

Association of mu-opioid receptor subunit gene and idiopathic generalized epilepsy.

Wilkie H et al.

Neurology, 2002

A polymorphism (A118G) in the mu-opioid receptor gene affects the response to morphine-6-glucuronide in humans.

Höllt V

Pharmacogenetics, 2002

Bioinformatic analysis of the human mu opioid receptor (OPRM1) splice and polymorphic variants.

Xin L et al.

Aaps Pharmsci, 2002

A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.

Befort K et al.

The Journal of Biological Chemistry, 2001

Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence.

Hoehe MR et al.

Human Molecular Genetics, 2000

Relevance of frequent mu-opioid receptor polymorphisms for opioid activity in healthy volunteers.

Lötsch J et al.

The Pharmacogenomics Journal, 0

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