Associated Papers
Whole exome/genome sequencing in cyclic vomiting syndrome reveals multiple candidate genes, suggesting a model of elevated intracellular cations and mitochondrial dysfunction.
Bar O et al.
Frontiers in Neurology, 2023
Novel variants of engineered water soluble mu opioid receptors with extensive mutations and removal of cysteines.
Xi J et al.
Proteins, 2021
Emergent biomarker derived from next-generation sequencing to identify pain patients requiring uncommonly high opioid doses.
Kringel D et al.
The Pharmacogenomics Journal, 2017
Convergent Balancing Selection on the Mu-Opioid Receptor in Primates.
Sweeney CG et al.
Molecular Biology and Evolution, 2017
Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1).
Knapman A et al.
British Journal of Pharmacology, 2015
Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.
Clarke TK et al.
Neuroscience Letters, 2013
Elucidation of mu-Opioid Gene Structure: How Genetics Can Help Predict Responses to Opioids.
Diatchenko L et al.
European Journal of Pain Supplements, 2011
Functional characterization of human variants of the mu-opioid receptor gene.
Ravindranathan A et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009
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