Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.G215Splc
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OPRM1

NM_000914.5:p.G215Splc

Associated Papers

μ-opioid receptor genetic polymorphisms and duration of epidural fentanyl analgesia during early labor.

Zgheib NK et al.

Minerva Anestesiologica, 2018

The Opposing Roles of IVS2+691 CC Genotype and AC/AG Diplotype of 118A>G and IVS2+691G>C of OPRM1 Polymorphisms in Cold Pain Tolerance Among Opioid-Dependent Malay Males on Methadone Therapy.

Zahari Z et al.

Pain and Therapy, 2015

Functional mu opioid receptor polymorphism (OPRM1 A(118) G) associated with heroin use outcomes in Caucasian males: A pilot study.

Woodcock EA et al.

The American Journal on Addictions, 2015

Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.

Rhodin A et al.

Molecular Brain, 2013

Association of polymorphisms in pharmacogenetic candidate genes (OPRD1, GAL, ABCB1, OPRM1) with opioid dependence in European population: a case-control study.

Beer B et al.

Plos One, 2013

Association of polymorphisms of the mu opioid receptor gene with the severity of HIV infection and response to HIV treatment.

Proudnikov D et al.

The Journal of Infectious Diseases, 2012

No evidence of association between 118A>G OPRM1 polymorphism and heroin dependence in a large Bulgarian case-control sample.

Nikolov MA et al.

Drug and Alcohol Dependence, 2011

Association between human opioid receptor genes polymorphisms and pressure pain sensitivity in females*.

Huang CJ et al.

Anaesthesia, 2008

Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence.

Zhang H et al.

Human Molecular Genetics, 2006

The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease.

Klepstad P et al.

Acta Anaesthesiologica Scandinavica, 2004

Sequence variations in the mu-opioid receptor gene (OPRM1) associated with human addiction to heroin.

Shi J et al.

Human Mutation, 2002

Bioinformatic analysis of the human mu opioid receptor (OPRM1) splice and polymorphic variants.

Xin L et al.

Aaps Pharmsci, 2002

Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence.

Hoehe MR et al.

Human Molecular Genetics, 2000

The role of genomic oxidative-reductive balance as predictor of complex regional pain syndrome development: a novel theory.

Smith HS

Pain Physician, 0

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