Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.E231Q
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OPRM1

NM_000914.5:p.E231Q

Associated Papers

A Pharmacogenomics-Based In Silico Investigation of Opioid Prescribing in Post-operative Spine Pain Management and Personalized Therapy.

Lewandrowski KU et al.

Cellular and Molecular Neurobiology, 2024

The Effect of Genetic Variation on the Sensitivity to Opioid Analgesics in Patients With Postoperative Pain: An Updated Meta-analysis.

Li ZX et al.

Pain Physician, 2023

Reviewing pharmacogenetics to advance precision medicine for opioids.

Magarbeh L et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2021

CYP2B6 and OPRM1 Receptor Polymorphisms at Methadone Clinics And Novel OPRM1 Haplotypes: A Cross-Sectional Study.

AlMeman AA et al.

Drug Metabolism Letters, 2016

Association between single nucleotide polymorphisms in the OPRM1 gene and intraoperative remifentanil consumption in northern Chinese women.

Liu J et al.

Pharmacology, 2014

Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside?

Mura E et al.

Journal of Pain Research, 2013

Analgesic requirements after major abdominal surgery are associated with OPRM1 gene polymorphism genotype and haplotype.

Hayashida M et al.

Pharmacogenomics, 2008

A functional polymorphism of the micro-opioid receptor gene is associated with completed suicides.

Hishimoto A et al.

Journal of Neural Transmission (vienna, Austria : 1996), 2008

[Genetic variation-- important for the clinical effect of opioids?].

Klepstad P et al.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, 2005

Genetic variability and clinical efficacy of morphine.

Klepstad P et al.

Acta Anaesthesiologica Scandinavica, 2005

The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease.

Klepstad P et al.

Acta Anaesthesiologica Scandinavica, 2004

Detection of single nucleotide polymorphisms of the human mu opioid receptor gene by hybridization or single nucleotide extension on custom oligonucleotide gelpad microchips: potential in studies of addiction.

LaForge KS et al.

American Journal of Medical Genetics, 2000

Linkage disequilibrium and association with methamphetamine dependence/psychosis of mu-opioid receptor gene polymorphisms.

Ide S et al.

The Pharmacogenomics Journal, 0

Relevance of frequent mu-opioid receptor polymorphisms for opioid activity in healthy volunteers.

Lötsch J et al.

The Pharmacogenomics Journal, 0

The impact of genetic variation on sensitivity to opioid analgesics in patients with postoperative pain: a systematic review and meta-analysis.

Ren ZY et al.

Pain Physician, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."