Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.R260H
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OPRM1

NM_000914.5:p.R260H

Associated Papers

Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort.

Åkerlund M et al.

Pain, 2025

The Influence of OPRM1 A118G Polymorphism on the Dosage of Morphine in Patients with Advanced Liver Cancer.

Cheng H et al.

Journal of the College of Physicians and Surgeons--pakistan : Jcpsp, 2021

Overview of Genetic Analysis of Human Opioid Receptors.

Spampinato SM

Methods in Molecular Biology (clifton, N.j.), 2021

Clinical and molecular characterization of COVID-19 hospitalized patients.

Benetti E et al.

Plos One, 2020

33206719 (PubMed )
Supplement: pone.0242534.s004.xlsx › Foglio1

Stabilization of μ-opioid receptor facilitates its cellular translocation and signaling.

Zhu C et al.

Proteins, 2019

Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1).

Knapman A et al.

British Journal of Pharmacology, 2015

Mu opioid receptor gene: new point mutations in opioid addicts.

Dinarvand A et al.

Basic and Clinical Neuroscience, 2014

Gene polymorphisms of OPRM1 A118G and ABCB1 C3435T may influence opioid requirements in Chinese patients with cancer pain.

Gong XD et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2013

Association of polymorphisms of the mu opioid receptor gene with the severity of HIV infection and response to HIV treatment.

Proudnikov D et al.

The Journal of Infectious Diseases, 2012

The genetics of the opioid system and specific drug addictions.

Levran O et al.

Human Genetics, 2012

Elucidation of mu-Opioid Gene Structure: How Genetics Can Help Predict Responses to Opioids.

Diatchenko L et al.

European Journal of Pain Supplements, 2011

The μ-opioid receptor variant N190K is unresponsive to peptide agonists yet can be rescued by small-molecule drugs.

Fortin JP et al.

Molecular Pharmacology, 2010

OPRM1 SNP (A118G): involvement in disease development, treatment response, and animal models.

Mague SD et al.

Drug and Alcohol Dependence, 2010

Novel linkage disequilibrium of single nucleotide polymorphisms in the transcriptional regulatory region of micro-opioid receptor gene in Japanese population.

Ono T et al.

Biological & Pharmaceutical Bulletin, 2009

Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.

Ryu GM et al.

Nucleic Acids Research, 2009

19139070 (PubMed )
Supplement: gkn1008_nar-01723-s-2008-File009.xls › TypeIII

Interindividual variability of methadone response: impact of genetic polymorphism.

Li Y et al.

Molecular Diagnosis & Therapy, 2008

[Are polymorphisms in the mu-opioid receptor important for opioid therapy?].

Lötsch J et al.

Schmerz (berlin, Germany), 2005

COMBINE genetics study: the pharmacogenetics of alcoholism treatment response: genes and mechanisms.

Goldman D et al.

Journal of Studies on Alcohol. Supplement, 2005

Gene polymorphisms of the mu opioid receptor in methamphetamine abusers.

Ide S et al.

Annals of the New York Academy of Sciences, 2004

Principles of pharmacogenetics--implications for the anaesthetist.

Iohom G et al.

British Journal of Anaesthesia, 2004

Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity?

Lötsch J et al.

Anesthesiology, 2002

A polymorphism (A118G) in the mu-opioid receptor gene affects the response to morphine-6-glucuronide in humans.

Höllt V

Pharmacogenetics, 2002

Bioinformatic analysis of the human mu opioid receptor (OPRM1) splice and polymorphic variants.

Xin L et al.

Aaps Pharmsci, 2002

Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding.

Wang D et al.

The Journal of Biological Chemistry, 2001

Detection of single nucleotide polymorphisms of the human mu opioid receptor gene by hybridization or single nucleotide extension on custom oligonucleotide gelpad microchips: potential in studies of addiction.

LaForge KS et al.

American Journal of Medical Genetics, 2000

Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction.

Bond C et al.

Proceedings of the National Academy of Sciences of the United States of America, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."