Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.K262R
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OPRM1

NM_000914.5:p.K262R

Associated Papers

Association of CYP2B6 and OPRM1 Genotypes with Methadone Dose Requirements and Serum Concentrations in a Vietnamese Cohorts.

Nguyen QG et al.

Balkan Journal of Medical Genetics : Bjmg, 2025

Combined Effect of CYP2B6 Genotype and Other Candidate Genes on a Steady-State Serum Concentration of Methadone in Opioid Maintenance Treatment.

Kringen MK et al.

Therapeutic Drug Monitoring, 2017

CYP2B6 SNPs are associated with methadone dose required for effective treatment of opioid addiction.

Levran O et al.

Addiction Biology, 2013

Worldwide variation in human drug-metabolism enzyme genes CYP2B6 and UGT2B7: implications for HIV/AIDS treatment.

Li J et al.

Pharmacogenomics, 2012

Interindividual variability in the prevalence of OPRM1 and CYP2B6 gene variations may identify drug-susceptible populations.

Bunten H et al.

Journal of Analytical Toxicology, 2011

Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response.

Fonseca F et al.

Plos One, 2011

OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths.

Bunten H et al.

Clinical Pharmacology and Therapeutics, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."